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WormBase Tree Display for Gene: WBGene00016570

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Name Class

WBGene00016570SMapS_parentSequenceC41G11
IdentityVersion2
NameCGC_namegnrr-4
Sequence_nameC41G11.4
Molecular_name (12)
Other_nameCELE_C41G11.4Accession_evidenceNDBBX284606
Public_namegnrr-4
DB_infoDatabaseAceViewgeneXG358
WormQTLgeneWBGene00016570
WormFluxgeneWBGene00016570
NDBlocus_tagCELE_C41G11.4
PanthergeneCAEEL|WormBase=WBGene00016570|UniProtKB=H2KZA0
familyPTHR24232
NCBIgene180841
RefSeqproteinNM_001373308.3
NM_171692.7
NM_001373309.4
NM_171954.7
TrEMBLUniProtAccH2KZ99
Q18564
A0A4V0ILV8
H2KZA0
UniProt_GCRPUniProtAccH2KZ99
OMIMgene609239
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
217 Aug 2007 13:50:11WBPerson2970Name_changeCGC_namegnrr-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgnrr
Allele (94)
StrainWBStrain00050889
RNASeq_FPKM (74)
GO_annotation00003949
00003950
00003951
00003952
00003953
00122151
00122152
00122153
Ortholog (86)
ParalogWBGene00008808Caenorhabditis elegansFrom_analysisTreeFam
WBGene00011582Caenorhabditis elegansFrom_analysisTreeFam
Structured_descriptionAutomated_descriptionPredicted to enable G protein-coupled receptor activity. Predicted to be involved in phospholipase C-activating G protein-coupled receptor signaling pathway and positive regulation of Rho protein signal transduction. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypotrichosis 8; and pre-eclampsia. Is an ortholog of several human genes including F2R (coagulation factor II thrombin receptor); F2RL1 (F2R like trypsin receptor 1); and GPR4 (G protein-coupled receptor 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110705Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:15520)
DOID:0060496Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3538)
DOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3538)
DOID:3083Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3538)
DOID:10591Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3537)
Molecular_infoCorresponding_CDSC41G11.4a
C41G11.4b
C41G11.4c
C41G11.4d
Corresponding_CDS_historyC41G11.4c:wp271
Corresponding_transcriptC41G11.4a.1
C41G11.4b.1
C41G11.4c.1
C41G11.4d.1
Other_sequenceJI180215.1
CBC02822_1
JO473585.1
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00042298Inferred_automaticallyRNAi_primary
WBRNAi00011838Inferred_automaticallyRNAi_primary
WBRNAi00029727Inferred_automaticallyRNAi_primary
WBRNAi00094990Inferred_automaticallyRNAi_primary
Expr_patternExpr1020910
Expr1146288
Expr2012161
Expr2030397
Drives_constructWBCnstr00027974
Construct_productWBCnstr00027974
Microarray_results (27)
Expression_cluster (91)
InteractionWBInteraction000316906
Map_infoMapXPosition-4.38087Error0.001677
PositivePositive_cloneC41G11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene