WormBase Tree Display for Gene: WBGene00016440
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WBGene00016440 | SMap | S_parent | Sequence | C35D10 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | gipc-1 | Person_evidence | WBPerson260 | |||||
Sequence_name | C35D10.2 | ||||||||
Molecular_name | C35D10.2 | ||||||||
C35D10.2.1 | |||||||||
CE01196 | |||||||||
Other_name | CELE_C35D10.2 | Accession_evidence | NDB | BX284603 | |||||
Public_name | gipc-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:57 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 07 Feb 2012 16:30:56 | WBPerson2970 | Name_change | CGC_name | gipc-1 | ||||
Status | Live | ||||||||
Gene_info (8) | |||||||||
Disease_info | Experimental_model | DOID:14330 | Homo sapiens | Paper_evidence | WBPaper00031384 | ||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 24 Jul 2013 00:00:00 | ||||||||
Potential_model | DOID:0110470 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:18183) | |||||
DOID:0081298 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1226) | ||||||
Disease_relevance | In an elegans model of Parkinson''s disease, where human alpha-synuclein was overexpressed, RNA interference studies showed that the elegans gipc-1/GIPC (GAIP-interacting protein, a conserved cellular scaffold-type protein), significantly protected against age- and dose-dependent degeneration in the dopamine neurons of transgenic worms; such models allow the identification of human modifier proteins of alpha-synuclein dependent misfolding and neurodegeneration, these proteins may also be new potential targets for therapeutic intervention. | Homo sapiens | Paper_evidence | WBPaper00031384 | |||||
Accession_evidence | OMIM | 605072 | |||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 24 Jul 2013 00:00:00 | ||||||||
Models_disease_in_annotation | WBDOannot00000214 | ||||||||
Molecular_info | Corresponding_CDS | C35D10.2 | |||||||
Corresponding_transcript | C35D10.2.1 | ||||||||
Other_sequence (16) | |||||||||
Associated_feature | WBsf976120 | ||||||||
WBsf224818 | |||||||||
Experimental_info | RNAi_result | WBRNAi00011661 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00022568 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00005097 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090599 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076199 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00041983 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00029578 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00001337 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram924 | ||||||||
Expr5437 | |||||||||
Expr15153 | |||||||||
Expr1022698 | |||||||||
Expr1145994 | |||||||||
Expr2012040 | |||||||||
Expr2030276 | |||||||||
Drives_construct | WBCnstr00002891 | ||||||||
WBCnstr00028069 | |||||||||
Construct_product | WBCnstr00006223 | ||||||||
WBCnstr00007333 | |||||||||
WBCnstr00028069 | |||||||||
Microarray_results (19) | |||||||||
Expression_cluster (288) | |||||||||
Interaction (224) | |||||||||
Map_info | Map | III | Position | -2.41286 | |||||
Positive | Positive_clone | C35D10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00027342 | ||||||||
WBPaper00031384 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00039525 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00056589 | |||||||||
WBPaper00060732 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |