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WormBase Tree Display for Gene: WBGene00015499

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Name Class

WBGene00015499SMapS_parentSequenceCHROMOSOME_I
IdentityVersion4
NameCGC_nameints-1Paper_evidenceWBPaper00040589
Person_evidenceWBPerson5934
Sequence_nameC06A5.1
Molecular_nameC06A5.1
C06A5.1.1
CE45602
Other_namelet-384Person_evidenceWBPerson533
inst-1
CELE_C06A5.1Accession_evidenceNDBBX284601
Public_nameints-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
209 Feb 2015 15:31:16WBPerson2970EventAcquires_mergeWBGene00002604
Name_changeCGC_nameinst-1
Other_namelet-384
306 Feb 2019 15:00:59WBPerson1983Name_changeCGC_nameints-1
Other_nameinst-1
420 May 2019 14:10:26WBPerson1983Name_changeCGC_nameints-1
Other_nameinst-1
Acquires_mergeWBGene00002604
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classints
Allele (107)
Legacy_information[McDowall JS] Sterile adult
[C.elegansII] h84 : late larval lethal or sterile adult. OA3: h388, h454, h865. [Howell et al. 1987; KR]
StrainWBStrain00023676
RNASeq_FPKM (74)
GO_annotation00024744
00024745
00121395
00121396
Contained_in_operonCEOP1288
Ortholog (34)
Structured_descriptionAutomated_descriptionPredicted to be involved in U2 snRNA 3'-end processing. Predicted to be part of integrator complex. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Is an ortholog of human INTS1 (integrator complex subunit 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070346Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:24555)
Molecular_infoCorresponding_CDSC06A5.1
Corresponding_CDS_historyC06A5.1:wp221
Corresponding_transcriptC06A5.1.1
Other_sequenceCBC11935_1
Associated_featureWBsf643327
WBsf656354
WBsf656355
WBsf217736
Experimental_infoRNAi_result (18)
Expr_patternExpr1013059
Expr1036631
Expr1143897
Expr2012783
Expr2031022
Drives_constructWBCnstr00028800
Construct_productWBCnstr00028800
Regulate_expr_clusterWBPaper00056284:ints-1(RNAi)_downregulated
WBPaper00056284:ints-1(RNAi)_upregulated
WBPaper00056284:ints-11(RNAi)_downregulated
WBPaper00056284:ints-11(RNAi)_upregulated
Microarray_results (20)
Expression_cluster (108)
Interaction (13)
Map_infoPositivePositive_cloneC06A5Inferred_automaticallyFrom sequence, transcript, pseudogene data
NegativeNegative_cloneC27D2
C32E7
C32G12
C40A4
C46H8
C48E7
Mapping_data2_point2548
Multi_point1034
Pos_neg_data2697
5545
5546
5547
5548
5700
4187
Interpolated_map_positionI0.673481
Reference (13)
Remark[McDowall JS] Extrachromosomal arrays containing three cosmids generated, then manipulated genetically.
MethodGene