WormBase Tree Display for Gene: WBGene00015391
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| WBGene00015391 | SMap | S_parent | Sequence | C03G5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sdha-1 | Paper_evidence | WBPaper00002116 | |||||
| Person_evidence | WBPerson4834 | ||||||||
| WBPerson4867 | |||||||||
| Sequence_name | C03G5.1 | ||||||||
| Molecular_name | C03G5.1 | ||||||||
| C03G5.1.1 | |||||||||
| CE03917 | |||||||||
| Other_name | CELE_C03G5.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | sdha-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 04 May 2006 14:27:47 | WBPerson2970 | Name_change | CGC_name | sdha-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sdha | ||||||||
| Allele (50) | |||||||||
| Possibly_affected_by | WBVar02154125 | ||||||||
| WBVar02154126 | |||||||||
| Strain | WBStrain00006137 | ||||||||
| WBStrain00001409 | |||||||||
| WBStrain00001419 | |||||||||
| WBStrain00036595 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00016392 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00018610 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | sdha-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA; OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. | Paper_evidence | WBPaper00004424 | |||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 11 Nov 2008 00:00:00 | ||||||||
| Automated_description | Contributes to succinate dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone. Located in mitochondrion. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Leigh disease; dilated cardiomyopathy 1GG; and mitochondrial complex II deficiency. Is an ortholog of human SDHA (succinate dehydrogenase complex flavoprotein subunit A). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060537 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10680) | ||||
| DOID:0110435 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10680) | ||||||
| DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10680) | ||||||
| DOID:14330 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10680) | ||||||
| DOID:3652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10680) | ||||||
| DOID:0050773 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10680) | ||||||
| Molecular_info | Corresponding_CDS | C03G5.1 | |||||||
| Corresponding_transcript | C03G5.1.1 | ||||||||
| Other_sequence (138) | |||||||||
| Associated_feature | WBsf654223 | ||||||||
| WBsf670850 | |||||||||
| WBsf982215 | |||||||||
| WBsf1006187 | |||||||||
| WBsf1006188 | |||||||||
| WBsf1006189 | |||||||||
| WBsf1023434 | |||||||||
| WBsf1023435 | |||||||||
| WBsf237698 | |||||||||
| WBsf237699 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern (16) | |||||||||
| Drives_construct | WBCnstr00001925 | ||||||||
| WBCnstr00002299 | |||||||||
| WBCnstr00002306 | |||||||||
| WBCnstr00004297 | |||||||||
| WBCnstr00004301 | |||||||||
| WBCnstr00028881 | |||||||||
| WBCnstr00041877 | |||||||||
| Construct_product | WBCnstr00028881 | ||||||||
| WBCnstr00041877 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (180) | |||||||||
| Interaction (194) | |||||||||
| Map_info | Map | X | Position | 0.101983 | Error | 0.001649 | |||
| Positive | Positive_clone | C03G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
