WormBase Tree Display for Gene: WBGene00013866
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WBGene00013866 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | cbs-1 | Paper_evidence | WBPaper00039977 | |||
Person_evidence | WBPerson537 | ||||||
Sequence_name | ZC373.1 | ||||||
Molecular_name | ZC373.1a | ||||||
ZC373.1a.1 | |||||||
CE31670 | |||||||
ZC373.1b | |||||||
CE47092 | |||||||
ZC373.1b.1 | |||||||
Other_name | CELE_ZC373.1 | Accession_evidence | NDB | BX284606 | |||
Public_name | cbs-1 | ||||||
DB_info | Database (12) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cbs | ||||||
Allele (32) | |||||||
Strain | WBStrain00002826 | ||||||
WBStrain00052082 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (16) | |||||||
Ortholog (40) | |||||||
Paralog (12) | |||||||
Structured_description | Concise_description | cbs-1 encodes an ortholog of human CYSTATHIONINE-BETA-SYNTHASE (CBS), which when mutated leads to homocystinuria (OMIM:236200). | Paper_evidence | WBPaper00004637 | |||
Curator_confirmed | WBPerson1823 | ||||||
WBPerson567 | |||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables cystathionine beta-synthase activity; cysteine synthase activity; and pyridoxal phosphate binding activity. Involved in sulfur compound biosynthetic process. Located in cytoplasm. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0080074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||
DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
DOID:9279 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
DOID:9263 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
Molecular_info | Corresponding_CDS | ZC373.1a | |||||
ZC373.1b | |||||||
Corresponding_CDS_history | ZC373.1:wp83 | ||||||
Corresponding_transcript | ZC373.1a.1 | ||||||
ZC373.1b.1 | |||||||
Other_sequence (40) | |||||||
Associated_feature | WBsf648441 | ||||||
WBsf655205 | |||||||
WBsf1006596 | |||||||
WBsf236234 | |||||||
Experimental_info | RNAi_result | WBRNAi00058845 | Inferred_automatically | RNAi_primary | |||
WBRNAi00091457 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (8) | |||||||
Drives_construct | WBCnstr00003351 | ||||||
WBCnstr00014401 | |||||||
WBCnstr00029491 | |||||||
Construct_product | WBCnstr00014401 | ||||||
WBCnstr00016327 | |||||||
WBCnstr00029491 | |||||||
Antibody | WBAntibody00002306 | ||||||
Microarray_results (22) | |||||||
Expression_cluster (173) | |||||||
Interaction (63) | |||||||
Map_info | Map | X | Position | 1.73547 | |||
Positive | Positive_clone | ZC373 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00034443 | ||||||
WBPaper00038491 | |||||||
WBPaper00040475 | |||||||
WBPaper00040626 | |||||||
WBPaper00055090 | |||||||
WBPaper00059856 | |||||||
WBPaper00059949 | |||||||
WBPaper00060431 | |||||||
WBPaper00060693 | |||||||
WBPaper00064989 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |