WormBase Tree Display for Gene: WBGene00013866
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WBGene00013866 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cbs-1 | Paper_evidence | WBPaper00039977 | |||||
Person_evidence | WBPerson537 | ||||||||
Sequence_name | ZC373.1 | ||||||||
Molecular_name | ZC373.1a | ||||||||
ZC373.1a.1 | |||||||||
CE31670 | |||||||||
ZC373.1b | |||||||||
CE47092 | |||||||||
ZC373.1b.1 | |||||||||
Other_name | CELE_ZC373.1 | Accession_evidence | NDB | BX284606 | |||||
Public_name | cbs-1 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 29 Sep 2011 10:45:56 | WBPerson2970 | Name_change | CGC_name | cbs-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cbs | ||||||||
Allele (32) | |||||||||
Strain | WBStrain00002826 | ||||||||
WBStrain00052082 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (16) | |||||||||
Ortholog (40) | |||||||||
Paralog (12) | |||||||||
Structured_description | Concise_description | cbs-1 encodes an ortholog of human CYSTATHIONINE-BETA-SYNTHASE (CBS), which when mutated leads to homocystinuria (OMIM:236200). | Paper_evidence | WBPaper00004637 | |||||
Curator_confirmed | WBPerson1823 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables cystathionine beta-synthase activity; cysteine synthase activity; and pyridoxal phosphate binding activity. Involved in sulfur compound biosynthetic process. Located in cytoplasm. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0080074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:9279 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:9263 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
Molecular_info (5) | |||||||||
Experimental_info | RNAi_result | WBRNAi00058845 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00091457 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (8) | |||||||||
Drives_construct | WBCnstr00003351 | ||||||||
WBCnstr00014401 | |||||||||
WBCnstr00029491 | |||||||||
Construct_product | WBCnstr00014401 | ||||||||
WBCnstr00016327 | |||||||||
WBCnstr00029491 | |||||||||
Antibody | WBAntibody00002306 | ||||||||
Microarray_results (22) | |||||||||
Expression_cluster (173) | |||||||||
Interaction (63) | |||||||||
Map_info | Map | X | Position | 1.73547 | |||||
Positive | Positive_clone | ZC373 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00034443 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00040475 | |||||||||
WBPaper00040626 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00059856 | |||||||||
WBPaper00059949 | |||||||||
WBPaper00060431 | |||||||||
WBPaper00060693 | |||||||||
WBPaper00064989 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |