WormBase Tree Display for Gene: WBGene00013866
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WBGene00013866 | SMap | S_parent | Sequence | CHROMOSOME_X | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | cbs | |||||
Allele (32) | ||||||
Strain | WBStrain00002826 | |||||
WBStrain00052082 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (16) | ||||||
Ortholog (40) | ||||||
Paralog (12) | ||||||
Structured_description | Concise_description | cbs-1 encodes an ortholog of human CYSTATHIONINE-BETA-SYNTHASE (CBS), which when mutated leads to homocystinuria (OMIM:236200). | Paper_evidence | WBPaper00004637 | ||
Curator_confirmed (2) | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
Automated_description | Enables cystathionine beta-synthase activity; cysteine synthase activity; and pyridoxal phosphate binding activity. Involved in sulfur compound biosynthetic process. Located in cytoplasm. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed (2) | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:0080074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | |
DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | |||
DOID:9279 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | |||
DOID:9263 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | |||
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | |||
DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | |||
Molecular_info | Corresponding_CDS | ZC373.1a | ||||
ZC373.1b | ||||||
Corresponding_CDS_history | ZC373.1:wp83 | |||||
Corresponding_transcript | ZC373.1a.1 | |||||
ZC373.1b.1 | ||||||
Other_sequence (40) | ||||||
Associated_feature | WBsf648441 | |||||
WBsf655205 | ||||||
WBsf1006596 | ||||||
WBsf236234 | ||||||
Experimental_info | RNAi_result | WBRNAi00058845 | Inferred_automatically | RNAi_primary | ||
WBRNAi00091457 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Chronogram1051 | |||||
Expr7160 | ||||||
Expr9921 | ||||||
Expr1018878 | ||||||
Expr1036202 | ||||||
Expr1162289 | ||||||
Expr2009744 | ||||||
Expr2027984 | ||||||
Drives_construct | WBCnstr00003351 | |||||
WBCnstr00014401 | ||||||
WBCnstr00029491 | ||||||
Construct_product | WBCnstr00014401 | |||||
WBCnstr00016327 | ||||||
WBCnstr00029491 | ||||||
Antibody | WBAntibody00002306 | |||||
Microarray_results (22) | ||||||
Expression_cluster (173) | ||||||
Interaction (63) | ||||||
Map_info | Map | X | Position | 1.73547 | ||
Positive | Positive_clone | ZC373 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference | WBPaper00034443 | |||||
WBPaper00038491 | ||||||
WBPaper00040475 | ||||||
WBPaper00040626 | ||||||
WBPaper00055090 | ||||||
WBPaper00059856 | ||||||
WBPaper00059949 | ||||||
WBPaper00060431 | ||||||
WBPaper00060693 | ||||||
WBPaper00064989 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |