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WormBase Tree Display for Gene: WBGene00012978

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Name Class

WBGene00012978SMapS_parentSequenceY48B6A
IdentityVersion1
NameSequence_nameY48B6A.1
Molecular_nameY48B6A.1
Y48B6A.1.1
CE22116
Other_nameCELE_Y48B6A.1Accession_evidenceNDBBX284602
Public_nameY48B6A.1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:54WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (89)
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (38)
Structured_descriptionConcise_descriptionY48B6A.1 encodes an ortholog of human BOP1 (OMIM:610596, overexpressed in colon cancer) and S. cerevisiae ERB1; Y48B6A.1 may suppress tumorous growth in the germ line by ensuring robust larval germline proliferation; like PRO-1, -2, and -3, Y48B6A.1 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germ line; however, BOP1 is also a phosphoprotein in mitotic spindles and required for normal chromosomal segregation, raising the possibility that Y48B6A.1 is multifunctional.Paper_evidenceWBPaper00028280
WBPaper00028938
WBPaper00028939
WBPaper00028940
WBPaper00028941
Curator_confirmedWBPerson567
Date_last_updated23 Apr 2008 00:00:00
Automated_descriptionPredicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Is an ortholog of human BOP1 (BOP1 ribosomal biogenesis factor).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY48B6A.1
Corresponding_transcriptY48B6A.1.1
Other_sequence (51)
Associated_featureWBsf650737
WBsf666358
WBsf990644
WBsf1013790
WBsf224249
WBsf224250
WBsf224251
Experimental_infoRNAi_resultWBRNAi00037227Inferred_automaticallyRNAi_primary
WBRNAi00056874Inferred_automaticallyRNAi_primary
WBRNAi00071234Inferred_automaticallyRNAi_primary
WBRNAi00009351Inferred_automaticallyRNAi_primary
WBRNAi00000309Inferred_automaticallyRNAi_primary
WBRNAi00103599Inferred_automaticallyRNAi_primary
WBRNAi00061475Inferred_automaticallyRNAi_primary
WBRNAi00026751Inferred_automaticallyRNAi_primary
WBRNAi00106940Inferred_automaticallyRNAi_primary
WBRNAi00094101Inferred_automaticallyRNAi_primary
Expr_patternExpr1023261
Expr1035756
Expr1160326
Expr2007658
Expr2025898
Microarray_results (18)
Expression_cluster (119)
Interaction (293)
Map_infoPositivePositive_cloneY48B6AInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII22.4539
ReferenceWBPaper00028280
WBPaper00038491
WBPaper00049828
WBPaper00055090
MethodGene