WormBase Tree Display for Gene: WBGene00010642

WBGene00010642 SMap: S_parent: Sequence: K07G5
  Identity: Version: 2
    Name: CGC_name: mks-6 Paper_evidence: WBPaper00035930
          Person_evidence: WBPerson2136
      Sequence_name: K07G5.3
      Molecular_name: K07G5.3
        K07G5.3.1
        CE06131
      Other_name: CELE_K07G5.3 Accession_evidence: NDB BX284601
      Public_name: mks-6
    DB_info: Database: AceView gene 1H741
        WormQTL gene WBGene00010642
        WormFlux gene WBGene00010642
        NDB locus_tag CELE_K07G5.3
        Panther gene CAEEL|WormBase=WBGene00010642|UniProtKB=Q21303
          family PTHR20837
        NCBI gene 187121
        RefSeq protein NM_059625.4
        TrEMBL UniProtAcc Q21303
        UniProt_GCRP UniProtAcc Q21303
        OMIM gene 612013
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 03 May 2011 10:00:42 WBPerson2970 Name_change: CGC_name: mks-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mks
    Allele (46)
    Strain: WBStrain00002458
      WBStrain00036618
    RNASeq_FPKM (74)
    GO_annotation (11)
    Contained_in_operon: CEOP1911
    Ortholog (39)
    Structured_description: Automated_description: Involved in non-motile cilium assembly and protein localization to ciliary transition zone. Located in ciliary transition zone and dendrite terminus. Expressed in ciliated neurons; head; and tail. Used to study ciliopathy. Human ortholog(s) of this gene implicated in several diseases, including Joubert syndrome 9; Meckel syndrome 6; and retinitis pigmentosa. Is an ortholog of human CC2D2A (coiled-coil and C2 domain containing 2A) and CC2D2B (coiled-coil and C2 domain containing 2B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:0060340
    Potential_model: DOID:0070120 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29253)
      DOID:0111004 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29253)
      DOID:10584 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29253)
      DOID:1059 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29253)
  Models_disease_asserted: WBDOannot00000306
  Molecular_info: Corresponding_CDS: K07G5.3
    Corresponding_transcript: K07G5.3.1
    Associated_feature: WBsf047483
      WBsf643428
      WBsf984111
      WBsf217958
  Experimental_info: RNAi_result: WBRNAi00034089 Inferred_automatically: RNAi_primary
      WBRNAi00003957 Inferred_automatically: RNAi_primary
      WBRNAi00050197 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1518
      Expr3732
      Expr6352
      Expr16117
      Expr1022997
      Expr1034652
      Expr1153893
      Expr2013586
      Expr2031819
    Drives_construct: WBCnstr00003055
      WBCnstr00011636
      WBCnstr00021215
      WBCnstr00031262
    Construct_product: WBCnstr00021215
      WBCnstr00031262
    Microarray_results (19)
    Expression_cluster (147)
    Interaction: WBInteraction000052312
      WBInteraction000296107
      WBInteraction000460286
      WBInteraction000553664
      WBInteraction000567455
  Map_info: Map: I Position: 1.8189 Error: 0.002931
    Positive: Positive_clone: K07G5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene