WormBase Tree Display for Gene: WBGene00008678
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| WBGene00008678 | SMap | S_parent | Sequence | F11A5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | stdh-2 | |||||||
| Sequence_name | F11A5.12 | ||||||||
| Molecular_name | F11A5.12 | ||||||||
| F11A5.12.1 | |||||||||
| CE15790 | |||||||||
| Other_name | dod-10 | ||||||||
| CELE_F11A5.12 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | stdh-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 25 Aug 2004 14:25:32 | WBPerson1971 | Name_change | CGC_name | stdh-2 | ||||
| Other_name | dod-10 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | stdh | ||||||||
| Allele (32) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00030698 | ||||||||
| 00030699 | |||||||||
| 00030700 | |||||||||
| 00030701 | |||||||||
| 00030702 | |||||||||
| Ortholog (68) | |||||||||
| Paralog (38) | |||||||||
| Structured_description | Concise_description | stdh-2 encodes a putative steroid dehydrogenase required for normally short lifespan; STDH-2 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767, STDH-1, and STDH-3/-4. | Paper_evidence | WBPaper00005976 | |||||
| WBPaper00006204 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 26 Nov 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||
| DOID:1923 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||||
| DOID:0112248 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||||
| Molecular_info | Corresponding_CDS | F11A5.12 | |||||||
| Corresponding_transcript | F11A5.12.1 | ||||||||
| Other_sequence | TV00027 | ||||||||
| CR05849 | |||||||||
| Tcol_isotig19572 | |||||||||
| TSC04652_1 | |||||||||
| TS00769 | |||||||||
| TS01447 | |||||||||
| TV00042 | |||||||||
| FK810039.1 | |||||||||
| CRC11005_1 | |||||||||
| TVC00958_1 | |||||||||
| Associated_feature | WBsf233085 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00030805 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00044347 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013104 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063181 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1148283 | ||||||||
| Expr2016957 | |||||||||
| Expr2035105 | |||||||||
| Drives_construct | WBCnstr00032778 | ||||||||
| Construct_product | WBCnstr00032778 | ||||||||
| Microarray_results (14) | |||||||||
| Expression_cluster (96) | |||||||||
| Interaction (65) | |||||||||
| Map_info | Map | V | Position | 9.85227 | Error | 0.001334 | |||
| Positive | Positive_clone | F11A5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005976 | ||||||||
| WBPaper00018598 | |||||||||
| WBPaper00032196 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
