WormBase Tree Display for Gene: WBGene00008386

WBGene00008386 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 3
    Name: CGC_name: cdc-5L Person_evidence: WBPerson1997
      Sequence_name: D1081.8
      Molecular_name: D1081.8
        D1081.8.1
        CE05540
      Other_name: phi-7 Person_evidence: WBPerson2582
        CELE_D1081.8 Accession_evidence: NDB BX284601
      Public_name: cdc-5L
    DB_info: Database: AceView gene 1J71
        WormQTL gene WBGene00008386
        WormFlux gene WBGene00008386
        NDB locus_tag CELE_D1081.8
        Panther gene CAEEL|WormBase=WBGene00008386|UniProtKB=G5EFC4
          family PTHR45885
        NCBI gene 172639
        RefSeq protein NM_059902.7
        TREEFAM TREEFAM_ID TF101061
        TrEMBL UniProtAcc G5EFC4
        UniProt_GCRP UniProtAcc G5EFC4
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 17 Mar 2005 13:54:35 WBPerson2970 Name_change: Other_name: phi-7
        3 03 Jul 2015 12:05:46 WBPerson2970 Name_change: CGC_name: cdc-5L
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cdc
    Allele (47)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Contained_in_operon: CEOP1929
    Ortholog (45)
    Paralog: WBGene00001568 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and spliceosomal complex. Human ortholog(s) of this gene implicated in esophagus adenocarcinoma and osteosarcoma. Is an ortholog of human CDC5L (cell division cycle 5 like). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3347 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1743)
      DOID:4914 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1743)
  Molecular_info: Corresponding_CDS: D1081.8
    Corresponding_transcript: D1081.8.1
    Other_sequence (57)
    Associated_feature: WBsf656637
      WBsf656638
      WBsf978468
      WBsf984449
      WBsf1010245
      WBsf218162
      WBsf218163
    Transcription_factor: WBTranscriptionFactor000978
  Experimental_info: RNAi_result (41)
    Expr_pattern: Expr10265
      Expr10266
      Expr1014947
      Expr1033634
      Expr1147404
      Expr1200042
      Expr2009789
      Expr2028029
    Drives_construct: WBCnstr00015215
      WBCnstr00033005
    Construct_product: WBCnstr00016699
      WBCnstr00033005
    Microarray_results (20)
    Expression_cluster (128)
    Interaction (230)
  Map_info: Map: I Position: 2.86796
    Positive: Positive_clone: D1081 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005736
    WBPaper00035228
    WBPaper00038491
    WBPaper00048493
    WBPaper00055090
    WBPaper00061547
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene