WormBase Tree Display for Gene: WBGene00008316

WBGene00008316 Evidence: Paper_evidence: WBPaper00005976
  SMap: S_parent: Sequence: C54G4
  Identity: Version: 2
    Name: CGC_name: dod-18 Person_evidence: WBPerson1157
      Sequence_name: C54G4.6
      Molecular_name: C54G4.6
        C54G4.6.1
        CE42082
      Other_name: CELE_C54G4.6 Accession_evidence: NDB BX284601
      Public_name: dod-18
    DB_info: Database: AceView gene 1I594
        WormQTL gene WBGene00008316
        WormFlux gene WBGene00008316
        NDB locus_tag CELE_C54G4.6
        Panther gene CAEEL|WormBase=WBGene00008316|UniProtKB=Q18851
          family PTHR43213
        NCBI gene 183813
        RefSeq protein NM_059804.3
        TREEFAM TREEFAM_ID TF342992
        TrEMBL UniProtAcc Q18851
        UniProt_GCRP UniProtAcc Q18851
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 25 Aug 2004 11:05:50 WBPerson1971 Name_change: CGC_name: dod-18
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dod
    Allele (19)
    Strain: WBStrain00032116
      WBStrain00050886
    RNASeq_FPKM (74)
    GO_annotation: 00062585
      00116257
    Ortholog (34)
    Structured_description: Concise_description: dod-18 encodes a Maf-like protein required for normally short lifespan;dod-18 is repressed in daf-2 mutants and induced in daf-16 mutants, anddod-18(RNAi) lengthens lifespan by 30%; MAF-like proteins are ubiquitousamong eukarya, bacteria, and archaea; DOD-18 is orthologous to theN-terminal ~200 residues of human ASMTL (OMIM:300162), and to Bacillussubtilis Maf (Multicopy Associated Filamentation) protein, whichinhibits septum formation; while the specific biochemical function ofMaf-like proteins is unknown, the tertiary structure of B. subtilis Mafis consistent with its binding nucleic acid. Paper_evidence: WBPaper00005976
            WBPaper00029441
            WBPaper00029442
          Curator_confirmed: WBPerson567
          Date_last_updated: 01 Jun 2007 00:00:00
      Automated_description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of human ASMTL (acetylserotonin O-methyltransferase like). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C54G4.6
    Corresponding_CDS_history: C54G4.6:wp187
    Corresponding_transcript: C54G4.6.1
    Other_sequence: Dviv_isotig27481
      Tcol_isotig16880
      CJC07590_1
      CBC14320_1
    Associated_feature: WBsf219854
      WBsf219855
  Experimental_info: RNAi_result: WBRNAi00063208 Inferred_automatically: RNAi_primary
      WBRNAi00063207 Inferred_automatically: RNAi_primary
      WBRNAi00003231 Inferred_automatically: RNAi_primary
      WBRNAi00043181 Inferred_automatically: RNAi_primary
      WBRNAi00116526 Inferred_automatically: RNAi_primary
      WBRNAi00063209 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1019440
      Expr1033604
      Expr1147159
      Expr2011015
      Expr2029253
    Drives_construct: WBCnstr00033062
    Construct_product: WBCnstr00033062
    Microarray_results (19)
    Expression_cluster (73)
    Interaction (40)
  Map_info: Map: I Position: 2.4212 Error: 0.000766
    Positive: Positive_clone: C54G4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005976
    WBPaper00038491
    WBPaper00055090
    WBPaper00064339
    WBPaper00064934
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene