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WormBase Tree Display for Gene: WBGene00007443

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Name Class

WBGene00007443SMapS_parentSequenceC08F8
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classpfd
Allele (15)
StrainWBStrain00027643
WBStrain00027644
WBStrain00002703
WBStrain00036248
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP4420
Ortholog (29)
Structured_descriptionConcise_descriptionpfd-1 encodes a putative prefoldin subunit 1, orthologous to human PFDN1 (OMIM:604897), that is required for normal microtubule nucleation and growth, embryonic viability, distal tip cell (DTC) migration, and locomotion; PFD-1 is expressed cytoplasmically in most, if not all, tissues; pfd-1(RNAi) animals have sterile progeny and are uncoordinated, and pfd-1(RNAi) embryos show a reduced microtubule growth rate; pfd-1(gk526) or escaper pfd-1(RNAi) hermaphrodites exhibit detective DTC migration.Paper_evidenceWBPaper00004651
WBPaper00005654
WBPaper00006395
WBPaper00024497
WBPaper00026660
WBPaper00031309
WBPaper00031362
WBPaper00031363
Curator_confirmedWBPerson567
Date_last_updated14 Jan 2008 00:00:00
Automated_descriptionPredicted to enable protein folding chaperone and unfolded protein binding activity. Involved in gonad development. Located in cytoplasm. Expressed in head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN1 (prefoldin subunit 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC08F8.1a
C08F8.1b
Corresponding_transcriptC08F8.1a.1
C08F8.1b.1
Other_sequence (24)
Associated_featureWBsf646357
WBsf229107
Experimental_infoRNAi_result (34)
Expr_patternExpr5210
Expr7839
Expr7844
Expr9564
Expr1028881
Expr1033205
Expr1144198
Expr2014841
Expr2033076
Drives_constructWBCnstr00001362
WBCnstr00001364
WBCnstr00003245
WBCnstr00033735
Construct_productWBCnstr00033735
Microarray_results (22)
Expression_cluster (83)
Interaction (26)
Map_info (3)
ReferenceWBPaper00031309
WBPaper00038444
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene