WormBase Tree Display for Gene: WBGene00007443
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WBGene00007443 | SMap | S_parent | Sequence | C08F8 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | pfd-1 | Person_evidence | WBPerson2136 | |||
WBPerson3663 | |||||||
Sequence_name | C08F8.1 | ||||||
Molecular_name | C08F8.1a | ||||||
C08F8.1a.1 | |||||||
CE05248 | |||||||
C08F8.1b | |||||||
CE45776 | |||||||
C08F8.1b.1 | |||||||
Other_name | CELE_C08F8.1 | Accession_evidence | NDB | BX284604 | |||
Public_name | pfd-1 | ||||||
DB_info | Database | AceView | gene | 4L915 | |||
WormQTL | gene | WBGene00007443 | |||||
WormFlux | gene | WBGene00007443 | |||||
NDB | locus_tag | CELE_C08F8.1 | |||||
Panther | gene | CAEEL|WormBase=WBGene00007443|UniProtKB=Q17827 | |||||
family | PTHR20903 | ||||||
NCBI | gene | 178021 | |||||
RefSeq | protein | NM_001268612.4 | |||||
NM_001268611.4 | |||||||
SwissProt | UniProtAcc | Q17827 | |||||
TREEFAM | TREEFAM_ID | TF106490 | |||||
UniProt_GCRP | UniProtAcc | Q17827 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | pfd | ||||||
Allele (15) | |||||||
Strain | WBStrain00027643 | ||||||
WBStrain00027644 | |||||||
WBStrain00002703 | |||||||
WBStrain00036248 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (13) | |||||||
Contained_in_operon | CEOP4420 | ||||||
Ortholog (29) | |||||||
Structured_description | Concise_description | pfd-1 encodes a putative prefoldin subunit 1, orthologous to human PFDN1 (OMIM:604897), that is required for normal microtubule nucleation and growth, embryonic viability, distal tip cell (DTC) migration, and locomotion; PFD-1 is expressed cytoplasmically in most, if not all, tissues; pfd-1(RNAi) animals have sterile progeny and are uncoordinated, and pfd-1(RNAi) embryos show a reduced microtubule growth rate; pfd-1(gk526) or escaper pfd-1(RNAi) hermaphrodites exhibit detective DTC migration. | Paper_evidence | WBPaper00004651 | |||
WBPaper00005654 | |||||||
WBPaper00006395 | |||||||
WBPaper00024497 | |||||||
WBPaper00026660 | |||||||
WBPaper00031309 | |||||||
WBPaper00031362 | |||||||
WBPaper00031363 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 14 Jan 2008 00:00:00 | ||||||
Automated_description | Predicted to enable protein folding chaperone and unfolded protein binding activity. Involved in gonad development. Located in cytoplasm. Expressed in head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN1 (prefoldin subunit 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C08F8.1a | |||||
C08F8.1b | |||||||
Corresponding_transcript | C08F8.1a.1 | ||||||
C08F8.1b.1 | |||||||
Other_sequence (24) | |||||||
Associated_feature | WBsf646357 | ||||||
WBsf229107 | |||||||
Experimental_info | RNAi_result (34) | ||||||
Expr_pattern | Expr5210 | ||||||
Expr7839 | |||||||
Expr7844 | |||||||
Expr9564 | |||||||
Expr1028881 | |||||||
Expr1033205 | |||||||
Expr1144198 | |||||||
Expr2014841 | |||||||
Expr2033076 | |||||||
Drives_construct (4) | |||||||
Construct_product | WBCnstr00033735 | ||||||
Microarray_results (22) | |||||||
Expression_cluster (83) | |||||||
Interaction (26) | |||||||
Map_info | Map | IV | Position | 4.91006 | Error | 0.00115 | |
Positive | Positive_clone | C08F8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00031309 | ||||||
WBPaper00038444 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |