WormBase Tree Display for Gene: WBGene00006538
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WBGene00006538 | SMap | S_parent | Sequence | B0272 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | tbb-4 | |||||||
Sequence_name | B0272.1 | ||||||||
Molecular_name | B0272.1 | ||||||||
B0272.1.1 | |||||||||
CE00850 | |||||||||
Other_name | CELE_B0272.1 | Accession_evidence | NDB | BX284606 | |||||
Public_name | tbb-4 | ||||||||
DB_info | Database | AceView | gene | XK54 | |||||
WormQTL | gene | WBGene00006538 | |||||||
WormFlux | gene | WBGene00006538 | |||||||
NDB | locus_tag | CELE_B0272.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00006538|UniProtKB=P41937 | |||||||
family | PTHR11588 | ||||||||
NCBI | gene | 181170 | |||||||
RefSeq | protein | NM_077184.8 | |||||||
SwissProt | UniProtAcc | P41937 | |||||||
UniProt_GCRP | UniProtAcc | P41937 | |||||||
OMIM | gene | 191130 | |||||||
602660 | |||||||||
602662 | |||||||||
612850 | |||||||||
615101 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | tbb | ||||||||
Allele (60) | |||||||||
Strain | WBStrain00034387 | ||||||||
WBStrain00036287 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (19) | |||||||||
Ortholog (57) | |||||||||
Paralog (16) | |||||||||
Structured_description | Automated_description | Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in axonemal microtubule. Expressed in HSN; accessory cell; epithelial cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Leber congenital amaurosis with early-onset deafness; complex cortical dysplasia with other brain malformations (multiple); and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB4B (tubulin beta 4B class IVb). | Paper_evidence | WBPaper00065943 | |||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0112242 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20778) | ||||
DOID:0090136 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20778) | ||||||
DOID:0112240 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20771) | ||||||
DOID:0090135 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12412) | ||||||
DOID:0060798 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20774) | ||||||
DOID:0090132 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:30829) | ||||||
DOID:0090041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20774) | ||||||
Molecular_info | Corresponding_CDS | B0272.1 | |||||||
Corresponding_transcript | B0272.1.1 | ||||||||
Other_sequence (86) | |||||||||
Associated_feature (15) | |||||||||
Experimental_info | RNAi_result | WBRNAi00066661 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076044 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00080510 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00038824 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00009643 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00028040 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00007393 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (13) | |||||||||
Drives_construct | WBCnstr00006863 | ||||||||
WBCnstr00006865 | |||||||||
WBCnstr00006866 | |||||||||
WBCnstr00011041 | |||||||||
WBCnstr00013859 | |||||||||
WBCnstr00013863 | |||||||||
WBCnstr00019056 | |||||||||
WBCnstr00034315 | |||||||||
Construct_product | WBCnstr00001230 | ||||||||
WBCnstr00006863 | |||||||||
WBCnstr00013863 | |||||||||
WBCnstr00014887 | |||||||||
WBCnstr00019056 | |||||||||
WBCnstr00021863 | |||||||||
WBCnstr00034315 | |||||||||
Microarray_results (20) | |||||||||
Expression_cluster (234) | |||||||||
Interaction (232) | |||||||||
Map_info | Map | X | Position | 1.209 | Error | 0.018453 | |||
Positive | Positive_clone | B0272 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | 2_point | 7013 | |||||||
Multi_point | 5208 | ||||||||
4333 | |||||||||
4587 | |||||||||
Pseudo_map_position | |||||||||
Reference (30) | |||||||||
Remark | cgc3909 linked tbb-4 to K01G5.7, which is not approved by CGC | CGC_data_submission | |||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |