WormBase Tree Display for Gene: WBGene00006452
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WBGene00006452 | SMap | S_parent | Sequence | R148 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | heh | ||||||
Allele (19) | |||||||
Strain | WBStrain00003220 | ||||||
WBStrain00022846 | |||||||
WBStrain00035732 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00029566 | ||||||
00029567 | |||||||
00029568 | |||||||
00029569 | |||||||
00114094 | |||||||
00114095 | |||||||
Ortholog (37) | |||||||
Structured_description | Concise_description | tag-79/R148.6 is orthologous to human NPC2 (OMIM:601015, mutated in Niemann-Pick disease type C2) | Curator_confirmed | WBPerson1823 | |||
WBPerson567 | |||||||
Date_last_updated | 09 Aug 2004 00:00:00 | ||||||
Automated_description | Predicted to enable sterol binding activity. Predicted to be involved in sterol transport. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in Niemann-Pick disease type C2. Is an ortholog of human NPC2 (NPC intracellular cholesterol transporter 2). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:14504 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14537) | ||
DOID:0070114 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14537) | ||||
Molecular_info | Corresponding_CDS | R148.6 | |||||
Corresponding_transcript | R148.6.1 | ||||||
Associated_feature | WBsf1014525 | ||||||
WBsf226325 | |||||||
Experimental_info (6) | |||||||
Map_info | Map | III | Position | -7.40298 | Error | 0.018291 | |
Positive | Positive_clone | R148 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4491 | |||||
5488 | |||||||
5622 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00024084 | ||||||
WBPaper00038491 | |||||||
WBPaper00042257 | |||||||
WBPaper00053559 | |||||||
WBPaper00055090 | |||||||
Remark | Gene name created from parsing 'genotype' field from CGC strain information | CGC_data_submission | |||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |