WormBase Tree Display for Gene: WBGene00004793
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| WBGene00004793 | SMap | S_parent | Sequence | R186 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | shw-3 | Person_evidence | WBPerson655 | |||||
| Sequence_name | R186.5 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | kht-1 | Paper_evidence | WBPaper00033073 | ||||||
| CELE_R186.5 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | shw-3 | ||||||||
| DB_info | Database | AceView | gene | 5N454 | |||||
| WormQTL | gene | WBGene00004793 | |||||||
| WormFlux | gene | WBGene00004793 | |||||||
| NDB | locus_tag | CELE_R186.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004793|UniProtKB=A0A3B1E007 | |||||||
| family | PTHR11537 | ||||||||
| NCBI | gene | 191761 | |||||||
| RefSeq | protein | NM_001380790.1 | |||||||
| NM_001380791.1 | |||||||||
| NM_001368471.3 | |||||||||
| TrEMBL | UniProtAcc | A0A3B1DVP6 | |||||||
| G5EEK7 | |||||||||
| A0A3B1E007 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A3B1E007 | |||||||
| OMIM | gene | 176256 | |||||||
| 176258 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | shw | ||||||||
| Allele (197) | |||||||||
| Legacy_information | [Thomas JH] shw for Shaw-like potassium channel. Predicted gene R186.5 | ||||||||
| Strain | WBStrain00032252 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (31) | |||||||||
| Ortholog (42) | |||||||||
| Paralog (13) | |||||||||
| Structured_description | Automated_description | Enables voltage-gated potassium channel activity. Involved in potassium ion transport. Located in axolemma; dendrite membrane; and neuronal cell body membrane. Expressed in PLML; PLMR; head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; electroclinical syndrome (multiple); and glioblastoma. Is an ortholog of human KCNC1 (potassium voltage-gated channel subfamily C member 1); KCNC2 (potassium voltage-gated channel subfamily C member 2); and KCNC4 (potassium voltage-gated channel subfamily C member 4). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6236) | ||||
| DOID:3068 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6234) | ||||||
| DOID:0070389 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6234) | ||||||
| DOID:0111447 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6233) | ||||||
| Molecular_info | Corresponding_CDS | R186.5a | |||||||
| R186.5b | |||||||||
| R186.5c | |||||||||
| Corresponding_CDS_history | R186.5:wp131 | ||||||||
| Corresponding_transcript | R186.5a.1 | ||||||||
| R186.5a.2 | |||||||||
| R186.5a.3 | |||||||||
| R186.5b.1 | |||||||||
| R186.5c.1 | |||||||||
| Other_sequence (14) | |||||||||
| Associated_feature | WBsf1001675 | ||||||||
| WBsf1001676 | |||||||||
| WBsf1001677 | |||||||||
| WBsf1001678 | |||||||||
| WBsf1020631 | |||||||||
| WBsf1020632 | |||||||||
| WBsf234758 | |||||||||
| WBsf234759 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00088724 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00017893 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00088617 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00034957 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052014 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8599 | ||||||||
| Expr8600 | |||||||||
| Expr12573 | |||||||||
| Expr1023253 | |||||||||
| Expr1032378 | |||||||||
| Expr1155654 | |||||||||
| Expr2015812 | |||||||||
| Expr2034045 | |||||||||
| Drives_construct | WBCnstr00013392 | ||||||||
| WBCnstr00035385 | |||||||||
| Construct_product | WBCnstr00021622 | ||||||||
| WBCnstr00035385 | |||||||||
| Antibody | WBAntibody00001905 | ||||||||
| Microarray_results (15) | |||||||||
| Expression_cluster (113) | |||||||||
| Interaction | WBInteraction000031710 | ||||||||
| WBInteraction000122640 | |||||||||
| WBInteraction000122877 | |||||||||
| WBInteraction000337432 | |||||||||
| WBInteraction000353898 | |||||||||
| WBInteraction000438346 | |||||||||
| WBInteraction000507360 | |||||||||
| WBInteraction000540010 | |||||||||
| WBInteraction000540828 | |||||||||
| WBInteraction000556253 | |||||||||
| Map_info | Map | V | Position | 4.7771 | Error | 0.001391 | |||
| Positive | Positive_clone | R186 | Person_evidence | WBPerson654 | |||||
| WBPerson655 | |||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005517 | ||||||||
| WBPaper00006402 | |||||||||
| WBPaper00022798 | |||||||||
| WBPaper00033073 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041802 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
