WormBase Tree Display for Gene: WBGene00004783
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| WBGene00004783 | SMap | S_parent | Sequence | Y73B6BL | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | seu-1 | Person_evidence | WBPerson893 | |||||
| Sequence_name | Y73B6BL.5 | ||||||||
| Molecular_name (15) | |||||||||
| Other_name | CELE_Y73B6BL.5 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | seu-1 | ||||||||
| DB_info | Database | AceView | gene | 4H97 | |||||
| WormQTL | gene | WBGene00004783 | |||||||
| WormFlux | gene | WBGene00004783 | |||||||
| NDB | locus_tag | CELE_Y73B6BL.5 | |||||||
| NCBI | gene | 177394 | |||||||
| RefSeq | protein | NM_068565.7 | |||||||
| NM_171359.5 | |||||||||
| NM_068564.7 | |||||||||
| NM_001380270.1 | |||||||||
| NM_001380269.2 | |||||||||
| SwissProt | UniProtAcc | A9D2P7 | |||||||
| UniProt_GCRP | UniProtAcc | A9D2P7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 07 Dec 2007 14:28:48 | WBPerson2970 | Event | Acquires_merge | WBGene00022234 | ||||
| Acquires_merge | WBGene00022234 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | seu | ||||||||
| Allele (53) | |||||||||
| Legacy_information | [Colavita A] suppressor of unc-5 induced dorsal guidance of the touch neurons, does not appear to have a visible phenotype | ||||||||
| Strain | WBStrain00029127 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00005452 | ||||||||
| 00005453 | |||||||||
| 00005454 | |||||||||
| 00005455 | |||||||||
| 00005456 | |||||||||
| Contained_in_operon | CEOP4176 | ||||||||
| Ortholog (18) | |||||||||
| Structured_description | Concise_description | seu-1 encodes three unfamiliar nuclear proteins by alternative splicing, at least two of which are required for completely normal signalling by UNC-6/netrin and its UNC-5 receptor; SEU-1 is also required for fully normal locomotion, body size and dauer formation; seu-1 mutations strongly suppress the misorientation of touch cell growth cones by ectopically expressed UNC-5, which otherwise would drive the touch cells to extend their processes dorsally; seu-1 mutations also strongly enhances distal tip cell (DTC) migration defects induced by ectopic UNC-40 in an unc-5(ev585) mutant background; SEU-1A/C are extensively composed of low-complexity regions that may form nonglobular domains, along with a charged central domain; SEU-1A/C are expressed in all embryonic nuclei until the comma stage, then becoming restricted to pharyngeal and muscle nuclei, with later expression persisting in muscle and expanding to intestinal cells, lateral hypodermal (seam) cells, Pn.p ventral hypodermal cells, spermatheca, and dorsally migrating DTCs; since seu-1 is transcribed both individually and as part of an operon, it may be expressed in cell types (such as touch neurons) other than those driven by its own local promoter; SEU-1A/B act cell-autonomously in touch neurons or DTCs, but both isoforms are needed for function. | Paper_evidence | WBPaper00003014 | |||||
| WBPaper00030970 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Nov 2007 00:00:00 | ||||||||
| Automated_description | Involved in dorsal/ventral axon guidance and locomotion. Located in nucleus. Expressed in several structures, including hermaphrodite distal tip cell; intestine; pharynx; spermatheca; and ventral nerve cord. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y73B6BL.5a | |||||||
| Y73B6BL.5b | |||||||||
| Y73B6BL.5c | |||||||||
| Y73B6BL.5d | |||||||||
| Y73B6BL.5e | |||||||||
| Corresponding_transcript | Y73B6BL.5a.1 | ||||||||
| Y73B6BL.5b.1 | |||||||||
| Y73B6BL.5c.1 | |||||||||
| Y73B6BL.5d.1 | |||||||||
| Y73B6BL.5e.1 | |||||||||
| Other_sequence | CBC05248_1 | ||||||||
| CBC07678_1 | |||||||||
| Associated_feature | WBsf660225 | ||||||||
| WBsf660226 | |||||||||
| WBsf660227 | |||||||||
| WBsf660228 | |||||||||
| WBsf660229 | |||||||||
| WBsf996727 | |||||||||
| WBsf996728 | |||||||||
| WBsf1017510 | |||||||||
| WBsf228400 | |||||||||
| WBsf228401 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00058343 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr7801 | ||||||||
| Expr1011219 | |||||||||
| Expr1032372 | |||||||||
| Expr1161760 | |||||||||
| Expr2015784 | |||||||||
| Expr2034017 | |||||||||
| Drives_construct | WBCnstr00012935 | ||||||||
| Construct_product | WBCnstr00012935 | ||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (75) | |||||||||
| SAGE_tag (18) | |||||||||
| Interaction | WBInteraction000052771 | ||||||||
| WBInteraction000574122 | |||||||||
| WBInteraction000576349 | |||||||||
| Map_info | Map | IV | Position | 3.1702 | Error | 0.001205 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | Y73B6BL | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 3527 | |||||||
| Reference | WBPaper00003014 | ||||||||
| WBPaper00004263 | |||||||||
| WBPaper00006185 | |||||||||
| WBPaper00010482 | |||||||||
| WBPaper00030970 | |||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
