WormBase Tree Display for Gene: WBGene00004358

WBGene00004358 SMap: S_parent: Sequence: F08F3
  Identity (6)
  Gene_info: Biotype: SO:0001217
    Gene_class: rhr
    Allele (35)
    Legacy_information: [Nettell J] rhr for Rh blood group antigen related. No mutants known. Predicted gene F08F3.3
    Strain: WBStrain00003312
      WBStrain00030768
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (52)
    Paralog: WBGene00000133 Caenorhabditis elegans From_analysis: Panther
      WBGene00000134 Caenorhabditis elegans From_analysis: Panther
      WBGene00000135 Caenorhabditis elegans From_analysis: Panther
      WBGene00000136 Caenorhabditis elegans From_analysis: Panther
      WBGene00004359 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: rhr-1 encodes an ortholog of human Rhesus blood-group associated glycoprotein (RHAG; OMIM:180297, mutated in chronic hemolytic anemia), a member of the ammonium transporter family, and affects general levels of mRNA transcripts, and embryonic viability in a large-scale RNAi screen. Paper_evidence: WBPaper00004651
            WBPaper00019491
          Curator_confirmed: WBPerson48
            WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables ammonium transmembrane transporter activity. Involved in ammonium transmembrane transport. Predicted to be located in plasma membrane. Expressed in head. Human ortholog(s) of this gene implicated in Rh deficiency syndrome; Rh isoimmunization; and overhydrated hereditary stomatocytosis. Is an ortholog of human RHAG (Rh associated glycoprotein); RHBG (Rh family B glycoprotein); and RHCG (Rh family C glycoprotein). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050641 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10006)
      DOID:4175 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10009)
      DOID:0111562 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10006)
      DOID:583 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10006)
  Molecular_info: Corresponding_CDS: F08F3.3
    Corresponding_transcript: F08F3.3.1
    Other_sequence (59)
    Associated_feature: WBsf231758
      WBsf231759
  Experimental_info: RNAi_result: WBRNAi00030654 Inferred_automatically: RNAi_primary
      WBRNAi00077594 Inferred_automatically: RNAi_primary
      WBRNAi00002398 Inferred_automatically: RNAi_primary
      WBRNAi00044017 Inferred_automatically: RNAi_primary
    Expr_pattern (9)
    Drives_construct: WBCnstr00002746
      WBCnstr00003783
      WBCnstr00035541
    Construct_product: WBCnstr00035541
    Microarray_results (22)
    Expression_cluster (237)
    Interaction (35)
  Map_info: Map: V Position: -2.02048 Error: 0.028616
    Positive: Positive_clone: F08F3 Author_evidence: Nettell JJ
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5216
        4182
        4348
    Pseudo_map_position
  Reference (9)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene