WormBase Tree Display for Gene: WBGene00004298
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WBGene00004298 | Evidence | CGC_data_submission | |||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | CHROMOSOME_I | ||||
Identity | Version | 2 | |||||
Name | CGC_name | rad-54.L | Person_evidence | WBPerson195 | |||
WBPerson1720 | |||||||
Sequence_name | W06D4.6 | ||||||
Molecular_name | W06D4.6 | ||||||
W06D4.6.1 | |||||||
CE25143 | |||||||
Other_name | rad-54 | ||||||
CELE_W06D4.6 | Accession_evidence | NDB | BX284601 | ||||
Public_name | rad-54.L | ||||||
DB_info | Database (11) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rad | ||||||
Allele (58) | |||||||
Strain | WBStrain00035848 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00016692 | ||||||
00016693 | |||||||
00016694 | |||||||
00016695 | |||||||
00016696 | |||||||
00016697 | |||||||
00016698 | |||||||
00112631 | |||||||
00112632 | |||||||
Ortholog (38) | |||||||
Paralog (19) | |||||||
Structured_description | Concise_description | rad-54 encodes a protein that belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, and human RAD54L, proteins known to be involved in the homologous recombination (HR) and repair of DNA; in elegans, rad-54 acts in a HR pathway, downstream of a nucleotide excision repair (NER) pathway, to promote ultraviolet induced apoptosis of damaged cells. | Paper_evidence | WBPaper00037879 | |||
WBPaper00035885 | |||||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 09 Sep 2013 00:00:00 | ||||||
Automated_description | Enables ATP-dependent activity, acting on DNA. Predicted to be involved in double-strand break repair via synthesis-dependent strand annealing and reciprocal meiotic recombination. Located in nucleus. Human ortholog(s) of this gene implicated in breast cancer; non-Hodgkin lymphoma; and pancreatic cancer. Is an ortholog of human RAD54L (RAD54 like). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0060060 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||
DOID:14566 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||
DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||
Molecular_info | Corresponding_CDS | W06D4.6 | |||||
Corresponding_transcript | W06D4.6.1 | ||||||
Other_sequence (33) | |||||||
Associated_feature | WBsf218248 | ||||||
Experimental_info | RNAi_result (21) | ||||||
Expr_pattern | Expr1013806 | ||||||
Expr1032124 | |||||||
Expr1158433 | |||||||
Expr2015242 | |||||||
Expr2033476 | |||||||
Drives_construct | WBCnstr00007713 | ||||||
WBCnstr00035582 | |||||||
Construct_product | WBCnstr00007713 | ||||||
WBCnstr00035582 | |||||||
Microarray_results (20) | |||||||
Expression_cluster (134) | |||||||
Interaction (103) | |||||||
Map_info | Map | I | Position | 3.48577 | Error | 0.010523 | |
Positive | Positive_clone | W06D4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (22) | |||||||
Remark | Sequence connection from [Boulton S, Vidal M] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |