WormBase Tree Display for Gene: WBGene00003569
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| WBGene00003569 | SMap | S_parent | Sequence | F35C12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ncx-4 | |||||||
| Sequence_name | F35C12.2 | ||||||||
| Molecular_name | F35C12.2a | ||||||||
| F35C12.2a.1 | |||||||||
| CE28020 | |||||||||
| F35C12.2b | |||||||||
| CE40052 | |||||||||
| F35C12.2b.1 | |||||||||
| Other_name | CELE_F35C12.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | ncx-4 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00003569 | |||||
| WormFlux | gene | WBGene00003569 | |||||||
| NDB | locus_tag | CELE_F35C12.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003569|UniProtKB=P90858 | |||||||
| family | PTHR10846 | ||||||||
| NCBI | gene | 172834 | |||||||
| RefSeq | protein | NM_001047199.4 | |||||||
| NM_001047198.5 | |||||||||
| TrEMBL | UniProtAcc | Q1ZXT5 | |||||||
| P90858 | |||||||||
| UniProt_GCRP | UniProtAcc | P90858 | |||||||
| OMIM | gene | 603617 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ncx | ||||||||
| Allele (48) | |||||||||
| Legacy_information | [Kraev A] ncx for Na/Ca eXchanger. No mutants known. See ncx-1. Predicted gene F35C12.2 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00003570 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ncx-4 encodes a putative 4Na[+]/1Ca[2+],1K[+] exchanger, orthologous to human SLC24A1-5 and paralogous to NCX-5; NCX-4 is predicted to export free cytoplasmic Ca[2+] with low affinity but high capacity, being complemented by low-capacity/high-affinity Ca[2+] ATPase pumps such as MCA-1/-3; NCX-4 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-4 has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00012774 | |||||
| WBPaper00028596 | |||||||||
| WBPaper00031156 | |||||||||
| WBPaper00031157 | |||||||||
| WBPaper00031158 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 07 Nov 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Predicted to be involved in calcium ion transmembrane transport and intracellular calcium ion homeostasis. Predicted to be located in membrane. Expressed in amphid neurons; labial sensillum; somatic nervous system; and tail neurons. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1D. Is an ortholog of human SLC24A1 (solute carrier family 24 member 1) and SLC24A2 (solute carrier family 24 member 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110868 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10975) | ||||
| Molecular_info | Corresponding_CDS | F35C12.2a | |||||||
| F35C12.2b | |||||||||
| Corresponding_CDS_history | F35C12.2:wp52 | ||||||||
| Corresponding_transcript | F35C12.2a.1 | ||||||||
| F35C12.2b.1 | |||||||||
| Other_sequence (39) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00046292 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00030218 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003587 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11158 | ||||||||
| Expr1010185 | |||||||||
| Expr1031627 | |||||||||
| Expr1150182 | |||||||||
| Expr2013921 | |||||||||
| Expr2032161 | |||||||||
| Drives_construct | WBCnstr00018018 | ||||||||
| WBCnstr00036036 | |||||||||
| Construct_product | WBCnstr00036036 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (182) | |||||||||
| Interaction (20) | |||||||||
| Map_info | Map | I | Position | 3.91252 | Error | 0.00076 | |||
| Positive | Positive_clone | F35C12 | Author_evidence | Kraev A | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003961 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062223 | |||||||||
| WBPaper00064552 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
