WormBase Tree Display for Gene: WBGene00003163
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| WBGene00003163 | SMap | S_parent | Sequence | R03E9 | |||
|---|---|---|---|---|---|---|---|
| Identity (6) | |||||||
| Gene_info (8) | |||||||
| Disease_info | Experimental_model | DOID:14330 | Homo sapiens | Paper_evidence | WBPaper00035654 | ||
| Curator_confirmed | WBPerson324 | ||||||
| Date_last_updated | 06 Jan 2014 00:00:00 | ||||||
| Potential_model | DOID:3512 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7534) | |||
| DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7534) | ||||
| Disease_relevance | mdl-1 encodes a bHLH (basic-helix-loop-helix) protein similar to the vertebrate MAD transcriptional regulators; mdl-1 is a candidate target gene for the small non-coding RNAs mir-64 and mir-65, and is found to be over-expressed in an transgenic elegans model for Parkinson''s disease, expressing human A53T alpha-synuclein, as well as in mir-64/mir-65 knock-out animals; mir-64 and mir-65 are co-underexpressed in the same model, suggesting a role for all of these genes in disease pathogenesis. | Homo sapiens | Paper_evidence | WBPaper00035654 | |||
| Curator_confirmed | WBPerson324 | ||||||
| Date_last_updated | 06 Jan 2014 00:00:00 | ||||||
| Models_disease_in_annotation | WBDOannot00000270 | ||||||
| Molecular_info | Corresponding_CDS | R03E9.1 | |||||
| Corresponding_transcript | R03E9.1.1 | ||||||
| Other_sequence (53) | |||||||
| Associated_feature (18) | |||||||
| Gene_product_binds (5628) | |||||||
| Transcription_factor | WBTranscriptionFactor000088 | ||||||
| WBTranscriptionFactor000010 | |||||||
| Experimental_info (8) | |||||||
| Map_info | Map | X | Position | -2.50858 | Error | 0.015767 | |
| Positive | Positive_clone | R03E9 | Author_evidence | Yuan JY | |||
| Cole MD | |||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Mapping_data | Multi_point | 4665 | |||||
| 5031 | |||||||
| Pseudo_map_position | |||||||
| Reference (28) | |||||||
| Remark | Data extracted from Yuan et al. (1998) | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
| Method | Gene |
