WormBase Tree Display for Gene: WBGene00002149
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WBGene00002149 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | irk | ||||||
Allele (170) | |||||||
Legacy_information | [Thomas JH] irk for Inward Rectifying potassium (K) channel family. | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (22) | |||||||
Ortholog (60) | |||||||
Paralog | WBGene00002150 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00002151 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Automated_description | Enables inward rectifier potassium channel activity. Involved in regulation of G protein-coupled receptor signaling pathway and regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in egg-laying apparatus; gonad; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); and KCNJ4 (potassium inwardly rectifying channel subfamily J member 4). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (16) | ||||||
Molecular_info | Corresponding_CDS | R03E9.4 | |||||
Corresponding_CDS_history | R03E9.4:wp230 | ||||||
Corresponding_transcript | R03E9.4.1 | ||||||
R03E9.4.2 | |||||||
Other_sequence (14) | |||||||
Associated_feature | WBsf1005634 | ||||||
WBsf1005635 | |||||||
WBsf1005636 | |||||||
WBsf1005637 | |||||||
WBsf1005638 | |||||||
WBsf1005639 | |||||||
WBsf1005640 | |||||||
WBsf1023138 | |||||||
WBsf1023139 | |||||||
Experimental_info | RNAi_result | WBRNAi00051184 | Inferred_automatically | RNAi_primary | |||
WBRNAi00017358 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr10594 | ||||||
Expr16175 | |||||||
Expr1023014 | |||||||
Expr1154892 | |||||||
Expr2012823 | |||||||
Expr2031061 | |||||||
Drives_construct | WBCnstr00015669 | ||||||
WBCnstr00017021 | |||||||
WBCnstr00042792 | |||||||
Construct_product | WBCnstr00015618 | ||||||
WBCnstr00015670 | |||||||
WBCnstr00015671 | |||||||
WBCnstr00015672 | |||||||
WBCnstr00015673 | |||||||
WBCnstr00017021 | |||||||
WBCnstr00042792 | |||||||
Microarray_results (22) | |||||||
Expression_cluster (103) | |||||||
Interaction (29) | |||||||
Map_info | Map | X | Position | -2.44289 | Error | 0.004144 | |
Positive | Positive_clone | R03E9 | Person_evidence | WBPerson654 | |||
WBPerson655 | |||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
Pseudo_map_position | |||||||
Reference | WBPaper00006402 | ||||||
WBPaper00028146 | |||||||
WBPaper00034195 | |||||||
WBPaper00038491 | |||||||
WBPaper00041734 | |||||||
WBPaper00049295 | |||||||
WBPaper00055090 | |||||||
WBPaper00060042 | |||||||
WBPaper00064330 | |||||||
Remark | irk-4 is the same as irk-1. Both Loci have now been merged into irk-1 with irk-4 just becoming an Other_name for this loci [krb 28/01/02] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |