WormBase Tree Display for Gene: WBGene00001782

WBGene00001782 Evidence: Person_evidence: WBPerson1846
  SMap: S_parent: Sequence: Y1H11
  Identity: Version: 1
    Name: CGC_name: gst-34
      Sequence_name: Y1H11.1
      Molecular_name: Y1H11.1
        Y1H11.1.1
        CE33336
      Other_name: CELE_Y1H11.1 Accession_evidence: NDB BX284602
      Public_name: gst-34
    DB_info: Database: AceView gene 2P464
        WormQTL gene WBGene00001782
        WormFlux gene WBGene00001782
        NDB locus_tag CELE_Y1H11.1
        Panther gene CAEEL|WormBase=WBGene00001782|UniProtKB=Q86S58
          family PTHR11571
        NCBI gene 260015
        RefSeq protein NM_171053.3
        TREEFAM TREEFAM_ID TF353041
        TrEMBL UniProtAcc Q86S58
        UniProt_GCRP UniProtAcc Q86S58
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gst
    Allele (56)
    RNASeq_FPKM (74)
    GO_annotation: 00083563
    Ortholog (28)
    Paralog (45)
    Structured_description: Automated_description: Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including juglone; metformin; and Sirolimus based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal; Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:2841 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4626)
      DOID:2394 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4626)
  Molecular_info: Corresponding_CDS: Y1H11.1
    Corresponding_CDS_history: Y1H11.1:wp88
      Y1H11.1:wp90
    Corresponding_transcript: Y1H11.1.1
    Other_sequence: Oden_contig05180
    Associated_feature: WBsf224323
  Experimental_info: RNAi_result: WBRNAi00055648 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022620
      Expr1159175
    Drives_construct: WBCnstr00036689
    Construct_product: WBCnstr00036689
    Microarray_results: A_12_P118684
      A_12_P169977
      A_12_P169978
      GPL14144_Y1H11.1_508-567_0.945_2_A
      GPL19516_CGZ0043461
      GPL21109_Y1H11.1
      GPL8304_CE_WBGene00001782_A
      GPL8673_Y1H11_1P00189
      GPL8673_Y1H11_1P00453
      GPL8673_Y1H11_1P00511
    Expression_cluster (70)
  Map_info: Map: II Position: 24.4203 Error: 0.014913
    Positive: Positive_clone: Y1H11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene