WormBase Tree Display for Gene: WBGene00001749
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WBGene00001749 | Evidence | Person_evidence | WBPerson1846 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | R107 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | gst | ||||||
Allele (13) | |||||||
Legacy_information | [C.elegansII] NMK. Encodes predicted glutathione-S-transferase P subunit. Transpliced to SL2. [Weston et al. 1989] | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (18) | |||||||
Contained_in_operon | CEOP3572 | ||||||
Ortholog (31) | |||||||
Paralog (45) | |||||||
Structured_description | Concise_description | gst-1 encodes a putative glutathione S-transferase of the pi class;GST-1 is required for sperm to normally migrate towards a PUFA-basedsignal exuded by oocytes; gst-1(RNAi) hermaphrodites are infertile,both through aberrant loss of their own sperm and through failure ofmales to effectively inseminate them. | Paper_evidence | WBPaper00028527 | |||
Curator_confirmed | WBPerson48 | ||||||
WBPerson567 | |||||||
Date_last_updated | 12 Mar 2007 00:00:00 | ||||||
Automated_description | Enables glutathione transferase activity. Involved in cellular detoxification; defense response to other organism; and regulation of cellular response to manganese ion. Predicted to be located in cytosol. Expressed in DA neuron. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (137) | ||||||
Molecular_info | Corresponding_CDS | R107.7 | |||||
Corresponding_transcript | R107.7.1 | ||||||
Other_sequence (57) | |||||||
Associated_feature | WBsf645457 | ||||||
WBsf645458 | |||||||
WBsf645459 | |||||||
WBsf981541 | |||||||
WBsf993558 | |||||||
WBsf225512 | |||||||
Experimental_info | RNAi_result (11) | ||||||
Expr_pattern | Expr11048 | ||||||
Expr1018206 | |||||||
Expr1031042 | |||||||
Expr1155346 | |||||||
Expr2012303 | |||||||
Expr2030539 | |||||||
Drives_construct | WBCnstr00019132 | ||||||
WBCnstr00036720 | |||||||
Construct_product | WBCnstr00036720 | ||||||
Antibody | WBAntibody00002442 | ||||||
Microarray_results (22) | |||||||
Expression_cluster (205) | |||||||
Interaction (46) | |||||||
Map_info | Map | III | Position | 0.129472 | Error | 0.002939 | |
Positive | Positive_clone | R107 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (23) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |