WormBase Tree Display for Gene: WBGene00001690
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WBGene00001690 | Evidence | Paper_evidence | WBPaper00003717 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | R08B4 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | grd | ||||||
Allele (93) | |||||||
Strain | WBStrain00035810 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (3) | |||||||
Ortholog (42) | |||||||
Paralog (24) | |||||||
Structured_description | Concise_description | grd-1 encodes a hedgehog-like protein, with (from N- to C-terminus) asignal sequence, a Ground domain, an extended region of low-complexitysequence, and a Hint/Hog domain; GRD-1 is expressed in rectal cells; theHint/Hog domain is predicted to cut GRD-1 into two halves and thencovalently link cholesterol to the C-terminus of the Ground domain; theGround domain is predicted to form a cysteine-crosslinked proteininvolved in intercellular signalling, and it has subtle similarity tothe N-terminal Hedge domain of HEDGEHOG proteins; GRD-1 is weaklyrequired for normal molting; GRD-1 is also required for normal growth tofull size, cuticle adhesion, and male tail development; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00003717 | |||
WBPaper00026841 | |||||||
WBPaper00027263 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson567 | |||||||
Date_last_updated | 05 Nov 2006 00:00:00 | ||||||
Automated_description | Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in extracellular region. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | R08B4.1 | |||||
Corresponding_CDS_history | R08B4.1:wp52 | ||||||
R08B4.1:wp83 | |||||||
R08B4.1:wp101 | |||||||
R08B4.1b:wp272 | |||||||
Corresponding_transcript | R08B4.1.1 | ||||||
R08B4.1.2 | |||||||
Other_sequence (17) | |||||||
Associated_feature | WBsf648520 | ||||||
WBsf648521 | |||||||
WBsf1023814 | |||||||
Experimental_info | RNAi_result | WBRNAi00076990 | Inferred_automatically | RNAi_primary | |||
WBRNAi00077015 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00051525 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00017576 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00111006 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr633 | ||||||
Expr4417 | |||||||
Expr1026738 | |||||||
Expr1031009 | |||||||
Expr1155201 | |||||||
Expr2012231 | |||||||
Expr2030467 | |||||||
Drives_construct | WBCnstr00011978 | ||||||
WBCnstr00012457 | |||||||
WBCnstr00036766 | |||||||
Construct_product | WBCnstr00036766 | ||||||
Microarray_results (27) | |||||||
Expression_cluster (197) | |||||||
Interaction | WBInteraction000114598 | ||||||
WBInteraction000114599 | |||||||
WBInteraction000114607 | |||||||
WBInteraction000173618 | |||||||
WBInteraction000237583 | |||||||
WBProcess | WBbiopr:00000123 | ||||||
Map_info | Map | X | Position | 2.85852 | Error | 0.000413 | |
Positive | Positive_clone | R08B4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4384 | |||||
4421 | |||||||
5511 | |||||||
Pseudo_map_position | |||||||
Reference (11) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |