WormBase Tree Display for Gene: WBGene00001410
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WBGene00001410 | SMap | S_parent | Sequence | Y54F10AM | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | feh | ||||||
Allele (248) | |||||||
Strain | WBStrain00003277 | ||||||
WBStrain00028627 | |||||||
WBStrain00028628 | |||||||
WBStrain00032616 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (14) | |||||||
Ortholog (39) | |||||||
Structured_description | Concise_description | feh-1 encodes the single C. elegans member of the Fe65 protein family that affects embryonic and larval viability and pharyngeal pumping; the PTB2 domain binds to cytosolic domain of C. elegans APL-1 in vitro; expressed in the neuromuscular structures of the pharynx and in a subset of neurons. | Paper_evidence | WBPaper00005169 | |||
Curator_confirmed | WBPerson48 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables amyloid-beta binding activity. Involved in embryo development; feeding behavior; and nematode larval development. Located in actin filament. Expressed in nerve ring; pharynx; tail neurons; and ventral cord neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease and cognitive disorder. Is an ortholog of human APBB2 (amyloid beta precursor protein binding family B member 2). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:581,HGNC:582) | ||
DOID:1561 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:582) | ||||
Molecular_info | Corresponding_CDS | Y54F10AM.2a | |||||
Y54F10AM.2b | |||||||
Y54F10AM.2c | |||||||
Y54F10AM.2d | |||||||
Corresponding_CDS_history | Y54F10AM.2c:wp143 | ||||||
Corresponding_transcript | Y54F10AM.2a.1 | ||||||
Y54F10AM.2b.1 | |||||||
Y54F10AM.2c.1 | |||||||
Y54F10AM.2c.2 | |||||||
Y54F10AM.2d.1 | |||||||
Y54F10AM.2d.2 | |||||||
Other_sequence (57) | |||||||
Associated_feature (21) | |||||||
Experimental_info | RNAi_result | WBRNAi00057399 | Inferred_automatically | RNAi_primary | |||
WBRNAi00063449 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00063448 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram110 | ||||||
Expr1865 | |||||||
Expr1866 | |||||||
Expr1020162 | |||||||
Expr1030844 | |||||||
Expr1160831 | |||||||
Expr2011748 | |||||||
Expr2029986 | |||||||
Drives_construct | WBCnstr00003748 | ||||||
WBCnstr00010495 | |||||||
Construct_product | WBCnstr00010495 | ||||||
Regulate_expr_cluster | WBPaper00031674:feh-1(gb561)(RNAi)_downregulated | ||||||
WBPaper00031674:feh-1(gb561)(RNAi)_upregulated | |||||||
Antibody | WBAntibody00000474 | ||||||
Microarray_results (27) | |||||||
Expression_cluster (224) | |||||||
Interaction (23) | |||||||
Map_info | Map | III | Position | -12.3627 | Error | 0.181296 | |
Positive | Positive_clone | Y54F10AM | Inferred_automatically (2) | ||||
Mapping_data | Multi_point | 4306 | |||||
4853 | |||||||
4820 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00005169 | ||||||
WBPaper00011375 | |||||||
WBPaper00024452 | |||||||
WBPaper00031506 | |||||||
WBPaper00031674 | |||||||
WBPaper00038491 | |||||||
WBPaper00039323 | |||||||
WBPaper00055090 | |||||||
WBPaper00064648 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |