WormBase Tree Display for Gene: WBGene00001137
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WBGene00001137 | SMap | S_parent | Sequence | B0365 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | eat | ||||||
Allele (46) | |||||||
Legacy_information (3) | |||||||
Strain | WBStrain00036106 | ||||||
WBStrain00037778 | |||||||
WBStrain00005464 | |||||||
WBStrain00005489 | |||||||
WBStrain00005507 | |||||||
WBStrain00005516 | |||||||
WBStrain00005529 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (36) | |||||||
Ortholog (46) | |||||||
Paralog (14) | |||||||
Structured_description | Concise_description | eat-6 encodes an ortholog of the alpha subunit of a sodium/potassium ATPase, which in turn affects Na+,K(+)-ATPase activity of membranes by affecting the level of the phosphorylated intermediate of the Na+,K(+)-ATPase; EAT-6 affects relaxation of the pharyngeal muscles, fertility (and thus affects feeding); EAT-6 also affects body length, life span, and ASE, ASI and ASJ axonal outgrowth. | Paper_evidence | WBPaper00001709 | |||
WBPaper00002371 | |||||||
WBPaper00003150 | |||||||
WBPaper00003257 | |||||||
WBPaper00003521 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson363 | |||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables P-type sodium:potassium-exchanging transporter activity. Involved in several processes, including action potential; monoatomic ion transport; and regulation of muscle contraction. Located in membrane. Expressed in several structures, including coelomocyte; intestine; neurons; pharynx; and vulval muscle. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2DD; alternating hemiplegia of childhood; and brain disease (multiple). Is an ortholog of human ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00045914 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 06 Jun 2019 00:00:00 | ||||||
Potential_model (12) | |||||||
Models_disease_asserted | WBDOannot00000704 | ||||||
Molecular_info | Corresponding_CDS | B0365.3 | |||||
Corresponding_transcript | B0365.3.1 | ||||||
B0365.3.2 | |||||||
Other_sequence (276) | |||||||
Associated_feature (18) | |||||||
Experimental_info | RNAi_result (34) | ||||||
Expr_pattern | Expr8226 | ||||||
Expr8228 | |||||||
Expr12845 | |||||||
Expr1017676 | |||||||
Expr1030726 | |||||||
Expr1143152 | |||||||
Expr2011160 | |||||||
Expr2029396 | |||||||
Drives_construct | WBCnstr00013194 | ||||||
WBCnstr00022897 | |||||||
WBCnstr00037068 | |||||||
Construct_product | WBCnstr00013192 | ||||||
WBCnstr00037068 | |||||||
Microarray_results (26) | |||||||
Expression_cluster (174) | |||||||
Interaction (116) | |||||||
Map_info | Map | V | Position | 4.93766 | Error | 0.013547 | |
Well_ordered | |||||||
Positive | Positive_clone | B0365 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
DF#NK1 | |||||||
R07B8 | |||||||
Mapping_data | 2_point | 5213 | |||||
Multi_point | 1837 | ||||||
1839 | |||||||
1840 | |||||||
1841 | |||||||
2403 | |||||||
2404 | |||||||
3844 | |||||||
4482 | |||||||
Pos_neg_data | 5212 | ||||||
5214 | |||||||
5215 | |||||||
7050 | |||||||
Reference (55) | |||||||
Remark | [MW Davis] Transformation rescue. | ||||||
Method | Gene |