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WormBase Tree Display for Gene: WBGene00001117

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Name Class

WBGene00001117SMapS_parentSequenceF54C1
IdentityVersion2
NameCGC_namedyf-1Person_evidenceWBPerson252
Sequence_nameF54C1.5
Molecular_nameF54C1.5a
F54C1.5a.1
CE33108
F54C1.5b
CE33109
F54C1.5b.1
F54C1.5b.2
F54C1.5b.3
F54C1.5b.4
Other_nameCELE_F54C1.5Accession_evidenceNDBBX284601
Public_namedyf-1
DB_infoDatabaseAceViewgene1F558
WormQTLgeneWBGene00001117
WormFluxgeneWBGene00001117
NDBlocus_tagCELE_F54C1.5
PanthergeneCAEEL|WormBase=WBGene00001117|UniProtKB=Q8I7G4
familyPTHR20931
NCBIgene172122
RefSeqproteinNM_059093.7
NM_182063.7
SwissProtUniProtAccQ8I7G4
TREEFAMTREEFAM_IDTF314592
UniProt_GCRPUniProtAccQ8I7G4
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
206 Oct 2005 14:32:56WBPerson2970EventAcquires_mergeWBGene00018790
Name_changeSequence_nameF54C1.5
Acquires_mergeWBGene00018790
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdyf
Allele (46)
Legacy_information[Herman RK] Defective in dye filling (FITC or DiO) of amphid and phasmid neurons. Chemotaxis defective. ME2
[C.elegansII] mn335mut : defective in dye filling (FITC or DiO) of amphid and phasmid neurons. Chemotaxis defective. ME2. [Starich et al. 1995]
Complementation_data[Herman RK] dyf-1(mn335) complements dyf-10(e1383) with respect to dye filling.
StrainWBStrain00034356
WBStrain00036821
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (42)
Structured_descriptionConcise_descriptiondyf-1 encodes a ciliary protein, belonging to a conserved but unfamiliarprotein family, specifically required for the kinesin OSM-3 to dock ontoand move intraflagellar transport (IFT) particles; DYF-1 affectsdevelopment of the amphid and phasmid neurons, chemotaxis, and dauerformation; DYF-1 function is downstream of BBS-8, which is required forIFT particles to stably bind both kinesin-II and OSM-3.Paper_evidenceWBPaper00002087
WBPaper00003661
WBPaper00004405
WBPaper00026666
Curator_confirmedWBPerson48
WBPerson567
Date_last_updated04 Dec 2006 00:00:00
Automated_descriptionPredicted to enable intraciliary transport particle B binding activity. Involved in intraciliary transport and protein localization to plasma membrane. Located in axonemal microtubule and ciliary basal body. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Is an ortholog of human IFT70A (intraflagellar transport 70A) and IFT70B (intraflagellar transport 70B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF54C1.5a
F54C1.5b
Corresponding_transcriptF54C1.5a.1
F54C1.5b.1
F54C1.5b.2
F54C1.5b.3
F54C1.5b.4
Other_sequence (17)
Associated_featureWBsf047479
WBsf649130
WBsf663796
WBsf664183
WBsf664184
WBsf664185
WBsf983569
WBsf983570
WBsf1009751
WBsf219350
Experimental_infoRNAi_resultWBRNAi00048247Inferred_automaticallyRNAi_primary
WBRNAi00032747Inferred_automaticallyRNAi_primary
WBRNAi00003766Inferred_automaticallyRNAi_primary
Expr_patternExpr3700
Expr3731
Expr1022891
Expr1030713
Expr1152052
Expr2011132
Expr2029368
Drives_constructWBCnstr00011612
WBCnstr00011635
WBCnstr00020273
WBCnstr00020994
WBCnstr00037076
WBCnstr00042566
WBCnstr00042567
Construct_productWBCnstr00011612
WBCnstr00037076
Regulate_expr_clusterWBPaper00064565:dyf-1(mn335)_downregulated
WBPaper00064565:dyf-1(mn335)_regulated_protein
WBPaper00064565:dyf-1(mn335)_upregulated
Microarray_results (23)
Expression_cluster (158)
InteractionWBInteraction000257029
WBInteraction000503954
WBInteraction000542897
WBInteraction000542909
WBInteraction000560434
WBInteraction000560436
WBInteraction000560438
WBInteraction000579031
WBInteraction000579033
Map_infoMapIPosition-0.429169Error0.000544
PositivePositive_cloneF54C1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point3035
3036
5501
Pos_neg_data8297
Reference (27)
MethodGene