WormBase Tree Display for Gene: WBGene00001093
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WBGene00001093 | SMap | S_parent | Sequence | T12E12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | drp-1 | Person_evidence | WBPerson733 | |||||
Sequence_name | T12E12.4 | ||||||||
Molecular_name | T12E12.4a | ||||||||
T12E12.4a.1 | |||||||||
CE30172 | |||||||||
T12E12.4b | |||||||||
CE30173 | |||||||||
T12E12.4a.2 | |||||||||
T12E12.4b.1 | |||||||||
T12E12.4b.2 | |||||||||
Other_name | CELE_T12E12.4 | Accession_evidence | NDB | BX284604 | |||||
Public_name | drp-1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | drp | ||||||||
Allele (45) | |||||||||
Strain | WBStrain00005196 | ||||||||
WBStrain00007389 | |||||||||
WBStrain00007408 | |||||||||
WBStrain00007414 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (30) | |||||||||
Contained_in_operon | CEOP4168 | ||||||||
Ortholog (39) | |||||||||
Paralog | WBGene00001134 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00001130 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | drp-1 encodes a dynamin-related protein, orthologous to Dnm1p in S. cerevisiae and DRP1 in mammals, that is required for severing of the mitochondrial outer membrane during mitochondrial division. | Paper_evidence | WBPaper00003790 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable GTP binding activity; GTPase activity; and microtubule binding activity. Involved in apoptotic mitochondrial changes; embryo development; and mitochondrial fission. Located in mitochondrion. Expressed in several structures, including germ line; non-striated muscle; preanal ganglion; rectal muscle; and somatic nervous system. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; encephalopathy due to defective mitochondrial and peroxisomal fission 1; optic atrophy 5; and pulmonary fibrosis. Is an ortholog of human DNM1L (dynamin 1 like). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed (2) | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Experimental_model | DOID:14330 | Homo sapiens | Paper_evidence | WBPaper00057005 | ||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 20 Feb 2020 00:00:00 | ||||||||
Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2973) | |||||
DOID:0070347 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2973) | ||||||
DOID:0111438 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2973) | ||||||
DOID:3770 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2973) | ||||||
Models_disease_asserted | WBDOannot00000741 | ||||||||
Molecular_info | Corresponding_CDS | T12E12.4a | |||||||
T12E12.4b | |||||||||
Corresponding_transcript | T12E12.4a.1 | ||||||||
T12E12.4a.2 | |||||||||
T12E12.4b.1 | |||||||||
T12E12.4b.2 | |||||||||
Other_sequence (72) | |||||||||
Associated_feature | WBsf655022 | ||||||||
WBsf660150 | |||||||||
WBsf981759 | |||||||||
WBsf996535 | |||||||||
WBsf228316 | |||||||||
WBsf228317 | |||||||||
WBsf228318 | |||||||||
Experimental_info | RNAi_result (36) | ||||||||
Expr_pattern | Expr543 | ||||||||
Expr11473 | |||||||||
Expr12437 | |||||||||
Expr1017306 | |||||||||
Expr1030697 | |||||||||
Expr1156803 | |||||||||
Expr2011094 | |||||||||
Expr2029330 | |||||||||
Drives_construct | WBCnstr00012431 | ||||||||
WBCnstr00037085 | |||||||||
Construct_product | WBCnstr00005418 | ||||||||
WBCnstr00005420 | |||||||||
WBCnstr00009299 | |||||||||
WBCnstr00012431 | |||||||||
WBCnstr00019040 | |||||||||
WBCnstr00037085 | |||||||||
Antibody | WBAntibody00001689 | ||||||||
Microarray_results (33) | |||||||||
Expression_cluster (152) | |||||||||
Interaction (114) | |||||||||
Map_info | Map | IV | Position | 1.82105 | Error | 0.005501 | |||
Positive | Positive_clone | T12E12 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (93) | |||||||||
Remark (2) | |||||||||
Method | Gene |