WormBase Tree Display for Gene: WBGene00000991
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WBGene00000991 | SMap | S_parent | Sequence | M03A8 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | dhs | ||||||
Allele (44) | |||||||
Strain | WBStrain00035626 | ||||||
WBStrain00040189 | |||||||
WBStrain00050737 | |||||||
WBStrain00050738 | |||||||
WBStrain00050736 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (16) | |||||||
Ortholog (37) | |||||||
Paralog (38) | |||||||
Structured_description | Concise_description | dhs-28 encodes an ortholog of human 17-BETA-HYDROXYSTEROID DEHYDROGENASE 4 (HSD17B4; OMIM:601860, mutated in D-bifunctional protein deficiency), which contains a C-terminal SCP-2 sterol transfer domain; the deletion allele dhs-28(ok450) is superficially wild-type. | Paper_evidence | WBPaper00004424 | |||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Predicted to enable oxidoreductase activity. Involved in several processes, including carbohydrate derivative metabolic process; dauer entry; and positive regulation of developmental process. Located in peroxisome. Expressed in hypodermis. Used to study obesity. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Is an ortholog of human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00035972 | ||
Curator_confirmed | WBPerson38202 | ||||||
Date_last_updated | 29 Jun 2018 00:00:00 | ||||||
Potential_model | DOID:13366 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5213) | |||
DOID:0090031 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5213) | ||||
DOID:0050857 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5213) | ||||
Models_disease_asserted | WBDOannot00000570 | ||||||
WBDOannot00000571 | |||||||
Molecular_info | Corresponding_CDS | M03A8.1 | |||||
Corresponding_transcript | M03A8.1.1 | ||||||
Other_sequence (107) | |||||||
Associated_feature | WBsf648263 | ||||||
WBsf648264 | |||||||
WBsf662918 | |||||||
WBsf235872 | |||||||
WBsf235873 | |||||||
Experimental_info | RNAi_result | WBRNAi00108444 | Inferred_automatically | RNAi_primary | |||
WBRNAi00008998 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00050847 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00034393 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00025981 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092604 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr8991 | ||||||
Expr1020554 | |||||||
Expr1030616 | |||||||
Expr1154542 | |||||||
Expr2010912 | |||||||
Expr2029151 | |||||||
Drives_construct | WBCnstr00013659 | ||||||
WBCnstr00037154 | |||||||
Construct_product (3) | |||||||
Antibody | WBAntibody00001955 | ||||||
WBAntibody00002918 | |||||||
Microarray_results (27) | |||||||
Expression_cluster (216) | |||||||
Interaction (99) | |||||||
Map_info | Map | X | Position | -2.40245 | Error | 0.010942 | |
Positive | Positive_clone | M03A8 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4258 | |||||
4343 | |||||||
5031 | |||||||
Pseudo_map_position | |||||||
Reference (31) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |