WormBase Tree Display for Gene: WBGene00000784
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WBGene00000784 | SMap | S_parent | Sequence | F44C4 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cpr | ||||||
Allele (33) | |||||||
Legacy_information | [C.elegansII] NMK. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm14e3). [IA] | ||||||
Strain | WBStrain00033148 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (16) | |||||||
Ortholog (44) | |||||||
Paralog (28) | |||||||
Structured_description | Concise_description | cpr-4 encodes a cathepsin B-like cysteine protease expressed at all life stages. | Paper_evidence | WBPaper00002373 | |||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables cysteine-type endopeptidase activity. Involved in cellular response to UV; cellular response to gamma radiation; and proteolysis involved in protein catabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed (2) | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:9351 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||
DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:2377 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:10941 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:12842 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:3068 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:4914 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2527) | ||||
Molecular_info | Corresponding_CDS | F44C4.3 | |||||
Corresponding_transcript | F44C4.3.1 | ||||||
Other_sequence (375) | |||||||
Associated_feature | WBsf646890 | ||||||
WBsf1000314 | |||||||
WBsf231894 | |||||||
Experimental_info | RNAi_result | WBRNAi00007344 | Inferred_automatically | RNAi_primary | |||
WBRNAi00115171 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00047258 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr741 | ||||||
Expr13281 | |||||||
Expr1014351 | |||||||
Expr1030485 | |||||||
Expr1151114 | |||||||
Expr2010505 | |||||||
Expr2028745 | |||||||
Drives_construct | WBCnstr00037278 | ||||||
WBCnstr00039152 | |||||||
Construct_product | WBCnstr00037278 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (354) | |||||||
Interaction (146) | |||||||
Map_info | Map | V | Position | 0.113422 | Error | 0.001009 | |
Positive | Positive_clone | F44C4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
W02B2 | Author_evidence | Larminie CGC | |||||
ZK1055 | |||||||
Pseudo_map_position | |||||||
Reference (15) | |||||||
Remark | data received 11/94 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |