WormBase Tree Display for Gene: WBGene00000561

WBGene00000561 Evidence: Paper_evidence: WBPaper00004409
  SMap: S_parent: Sequence: C34E10
  Identity: Version: 1
    Name: CGC_name: cnd-1 Person_evidence: WBPerson105
            WBPerson293
      Sequence_name: C34E10.7
      Molecular_name: C34E10.7
        C34E10.7.1
        CE01187
      Other_name: hlh-5 Person_evidence: WBPerson346
        C34E10.d Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        C34E10 Paper_evidence: WBPaper00027608
        CeND Paper_evidence: WBPaper00027608
        CELE_C34E10.7 Accession_evidence: NDB BX284603
      Public_name: cnd-1
    DB_info: Database: AceView gene 3G328
        WormQTL gene WBGene00000561
        WormFlux gene WBGene00000561
        OMIM disease 125853
            606394
          gene 601724
            601725
        NDB locus_tag CELE_C34E10.7
        Panther gene CAEEL|WormBase=WBGene00000561|UniProtKB=P46581
          family PTHR19290
        NCBI gene 183212
        RefSeq protein NM_001392092.1
        SwissProt UniProtAcc P46581
        UniProt_GCRP UniProtAcc P46581
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (9)
  Disease_info: Potential_model: DOID:9744 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7762)
      DOID:4195 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7762)
      DOID:10603 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7762)
      DOID:9970 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7762)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7762)
      DOID:0111104 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7762)
      DOID:0112208 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7763)
    Disease_relevance: In humans, mutations in Neurogenic Differentiation 1 (NeuroD1) have been implicated in Diabetes Mellitus, Type II and Maturity-onset diabetes of the young, type VI; in elegans, cnd-1, seems to have combined the function of several vertebrate neurogenic bHLH proteins, and is required for the proper fate specification and terminal differentiation of motor neurons. Homo sapiens Paper_evidence: WBPaper00004409
          Accession_evidence: OMIM 606394
              125853
              601724
          Curator_confirmed: WBPerson324
          Date_last_updated: 06 Sep 2013 00:00:00
  Molecular_info: Corresponding_CDS: C34E10.7
    Corresponding_transcript: C34E10.7.1
    Other_sequence: Dviv_isotig35392
      Dviv_isotig31167
      JI178639.1
      Tcol_isotig15910
    Associated_feature: WBsf651039
      WBsf666900
      WBsf978355
      WBsf992340
      WBsf992341
      WBsf226653
    Transcription_factor: WBTranscriptionFactor000076
      WBTranscriptionFactor000060
  Experimental_info (8)
  Map_info: Map: III Position: -1.85688 Error: 0.001135
    Positive: Positive_clone: C34E10 Inferred_automatically: From sequence, transcript, pseudogene data
        ZC129
    Mapping_data: 2_point: 7160
      Multi_point: 4094
      Pos_neg_data: 10730
  Reference (38)
  Remark: Postitive method is cosmid rescue Paper_evidence: WBPaper00004409
  Method: Gene