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WormBase Tree Display for Gene: WBGene00000433

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Name Class

WBGene00000433SMapS_parentSequenceZK265
IdentityVersion1
NameCGC_nameceh-8Person_evidenceWBPerson83
Sequence_nameZK265.4
Molecular_nameZK265.4a
ZK265.4a.1
CE38130
ZK265.4b
CE51184
ZK265.4c
CE51174
ZK265.4b.1
ZK265.4c.1
Other_nameCELE_ZK265.4Accession_evidenceNDBBX284601
Public_nameceh-8
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classceh
Allele (62)
Legacy_information[C.elegansII] NMK. Encodes homeoprotein. [Burglin et al. 1989]
StrainWBStrain00048956
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (41)
Paralog (20)
Structured_descriptionConcise_descriptionceh-8 encodes a paired-like homeodomain protein of the Q50 class orthologous to the Rx homeobox protein of humans (RAX; OMIM:601881) and Drosophila (CG10052-PA); CEH-8 and RX belong to one of at least 18 distinct families of paired-like homeodomain proteins, including 12 families in the Q50 class.Paper_evidenceWBPaper00004283
WBPaper00012756
WBPaper00012789
WBPaper00012805
WBPaper00013587
WBPaper00013612
WBPaper00021087
Curator_confirmedWBPerson48
WBPerson324
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in lateral ganglion and somatic gonad precursor. Human ortholog(s) of this gene implicated in isolated microphthalmia 3 and retinal degeneration (multiple). Is an ortholog of human RAX2 (retina and anterior neural fold homeobox 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060842Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18662)
DOID:0111018Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18286)
DOID:10584Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18286)
DOID:0110018Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18286)
Molecular_infoCorresponding_CDSZK265.4a
ZK265.4b
ZK265.4c
Corresponding_CDS_historyZK265.4:wp139
Corresponding_transcriptZK265.4a.1
ZK265.4b.1
ZK265.4c.1
Other_sequenceTS00310
FE911521.1
Acan_isotig07221
Oden_isotig22109
Dviv_isotig26408
FG355089.1
Associated_feature (11)
Transcription_factorWBTranscriptionFactor000341
Experimental_infoRNAi_resultWBRNAi00059317Inferred_automaticallyRNAi_primary
WBRNAi00038245Inferred_automaticallyRNAi_primary
WBRNAi00004920Inferred_automaticallyRNAi_primary
Expr_patternExpr12529
Expr15607
Expr1012028
Expr1030245
Expr1162746
Expr2009914
Expr2028154
Drives_constructWBCnstr00021456
WBCnstr00037543
Construct_productWBCnstr00037543
Microarray_results (19)
Expression_cluster (105)
Interaction (53)
Map_infoMapIPosition2.70293Error0.00034
PositivePositive_cloneXXD4
ZK265Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5076
4950
Pseudo_map_position
ReferenceWBPaper00001190
WBPaper00004283
WBPaper00015440
WBPaper00021087
WBPaper00027309
WBPaper00038491
WBPaper00048690
WBPaper00055090
WBPaper00060123
WBPaper00061738
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene