WormBase Tree Display for Gene: WBGene00000259
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| WBGene00000259 | Evidence | Person_evidence | WBPerson651 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F13H8 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | bpl-1 | Person_evidence | WBPerson651 | |||||
| Sequence_name | F13H8.10 | ||||||||
| Molecular_name (14) | |||||||||
| Other_name | CELE_F13H8.10 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | bpl-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | bpl | ||||||||
| Allele (85) | |||||||||
| Strain | WBStrain00033065 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00012878 | ||||||||
| 00012879 | |||||||||
| 00012880 | |||||||||
| 00107129 | |||||||||
| 00107130 | |||||||||
| Ortholog (38) | |||||||||
| Structured_description | Concise_description | bpl-1 encodes an ortholog of biotin ligase/holocarboxylase synthetase (called biotin ligase in bacteria, and holocarboxylase synthetase in mammalian or animal systems); it is orthologous to human HOLOCARBOXYLASE SYNTHETASE (HLCS; OMIM:253270), which when mutated leads to HLCS deficiency. | Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable biotin-[acetyl-CoA-carboxylase] ligase activity. Predicted to be involved in protein modification process. Predicted to be located in cytoplasm. Expressed in Psub1. Human ortholog(s) of this gene implicated in holocarboxylase synthetase deficiency. Is an ortholog of human HLCS (holocarboxylase synthetase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:859 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4976) | ||||
| Molecular_info | Corresponding_CDS | F13H8.10a | |||||||
| F13H8.10b | |||||||||
| F13H8.10c | |||||||||
| Corresponding_CDS_history | F13H8.10:wp84 | ||||||||
| F13H8.10a:wp193 | |||||||||
| Corresponding_transcript | F13H8.10a.1 | ||||||||
| F13H8.10b.1 | |||||||||
| F13H8.10c.1 | |||||||||
| F13H8.10c.2 | |||||||||
| F13H8.10c.3 | |||||||||
| F13H8.10c.4 | |||||||||
| F13H8.10c.5 | |||||||||
| F13H8.10c.6 | |||||||||
| Other_sequence (39) | |||||||||
| Associated_feature | WBsf644265 | ||||||||
| WBsf644266 | |||||||||
| WBsf644267 | |||||||||
| WBsf644268 | |||||||||
| WBsf657674 | |||||||||
| WBsf988120 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00044556 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr14403 | ||||||||
| Expr1011220 | |||||||||
| Expr1030167 | |||||||||
| Expr1148511 | |||||||||
| Expr2009643 | |||||||||
| Expr2027882 | |||||||||
| Drives_construct | WBCnstr00037622 | ||||||||
| Construct_product | WBCnstr00037622 | ||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (115) | |||||||||
| Interaction (36) | |||||||||
| Map_info | Map | II | Position | -0.390883 | Error | 0.000646 | |||
| Positive | Positive_clone | F13H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00046691 | |||||||||
| WBPaper00047153 | |||||||||
| WBPaper00053380 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00058165 | |||||||||
| WBPaper00064323 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
