WormBase Tree Display for Gene: WBGene00000074
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WBGene00000074 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | adm-2 | Person_evidence | WBPerson493 | |||||
Sequence_name | C04A11.4 | ||||||||
Molecular_name | C04A11.4a | ||||||||
C04A11.4a.1 | |||||||||
CE07906 | |||||||||
C04A11.4b | |||||||||
CE52805 | |||||||||
C04A11.4b.1 | |||||||||
Other_name | CELE_C04A11.4 | Accession_evidence | NDB | BX284606 | |||||
Public_name | adm-2 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | adm | ||||||||
Allele (182) | |||||||||
Strain | WBStrain00033018 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (17) | |||||||||
Ortholog (56) | |||||||||
Paralog | WBGene00006804 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00000075 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WormBase-Compara | |||||||||
WBGene00006324 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00016423 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00019514 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family); like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development. | Paper_evidence | WBPaper00002626 | |||||
WBPaper00012780 | |||||||||
WBPaper00012947 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to be located in endosome membrane; lysosomal membrane; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); endocrine gland cancer (multiple); and lung disease (multiple). Is an ortholog of human ADAM19 (ADAM metallopeptidase domain 19) and ADAM33 (ADAM metallopeptidase domain 33). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (18) | ||||||||
Molecular_info | Corresponding_CDS | C04A11.4a | |||||||
C04A11.4b | |||||||||
Corresponding_transcript | C04A11.4a.1 | ||||||||
C04A11.4b.1 | |||||||||
Other_sequence (12) | |||||||||
Associated_feature | WBsf663500 | ||||||||
WBsf1007698 | |||||||||
WBsf1007699 | |||||||||
WBsf1007700 | |||||||||
WBsf1007701 | |||||||||
WBsf1024282 | |||||||||
WBsf1024283 | |||||||||
WBsf1024284 | |||||||||
WBsf236598 | |||||||||
WBsf236599 | |||||||||
Experimental_info | RNAi_result (11) | ||||||||
Expr_pattern | Expr1014279 | ||||||||
Expr1030033 | |||||||||
Expr1143671 | |||||||||
Expr2009235 | |||||||||
Expr2027472 | |||||||||
Drives_construct | WBCnstr00037750 | ||||||||
Construct_product | WBCnstr00037750 | ||||||||
Microarray_results (18) | |||||||||
Expression_cluster (136) | |||||||||
Interaction (15) | |||||||||
Map_info | Map | X | Position | 14.3412 | Error | 0.068825 | |||
Positive | Positive_clone | C04A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4143 | |||||||
4898 | |||||||||
5297 | |||||||||
Pseudo_map_position | |||||||||
Reference (14) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |