WormBase Tree Display for Gene: WBGene00000066
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| WBGene00000066 | SMap | S_parent | Sequence | M03F4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | act-4 | Person_evidence | WBPerson259 | |||||
| Sequence_name | M03F4.2 | ||||||||
| Molecular_name | M03F4.2a | ||||||||
| M03F4.2a.1 | |||||||||
| CE12358 | |||||||||
| M03F4.2b | |||||||||
| CE28620 | |||||||||
| M03F4.2b.1 | |||||||||
| Other_name | act4 | Accession_evidence | EMBL | X16799 | |||||
| CELE_M03F4.2 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | act-4 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | act | ||||||||
| Allele (93) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes actin, similar to but distinct from actin-123. Abundant transcript. act-4::lacZ expressed strongly in body-wall muscles, vulval muscles, spermatheca. [Krause et al. 1989; Stone and Shaw 1993] | ||||||||
| Strain | WBStrain00007115 | ||||||||
| WBStrain00034753 | |||||||||
| WBStrain00052134 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (66) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | act-4 encodes an actin isoform that is most similar to act-2 in amino acid sequence; an act-4 reporter gene is expressed in body wall and vulval muscles and the spermatheca. | Paper_evidence | WBPaper00001178 | |||||
| WBPaper00014413 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 02 Apr 2007 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in actin cytoskeleton organization and mitotic cytokinesis. Located in striated muscle thin filament. Expressed in body wall musculature; gonad; spermatheca; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Is an ortholog of human ACTB (actin beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1588 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||
| DOID:0081113 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
| DOID:10881 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
| DOID:0081112 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
| DOID:0110550 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
| Molecular_info | Corresponding_CDS | M03F4.2a | |||||||
| M03F4.2b | |||||||||
| Corresponding_CDS_history | M03F4.2c:wp275 | ||||||||
| Corresponding_transcript | M03F4.2a.1 | ||||||||
| M03F4.2b.1 | |||||||||
| Other_sequence (822) | |||||||||
| Associated_feature (30) | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr590 | ||||||||
| Expr4555 | |||||||||
| Expr1026695 | |||||||||
| Expr1030027 | |||||||||
| Expr1154569 | |||||||||
| Expr1200203 | |||||||||
| Expr2009224 | |||||||||
| Expr2027461 | |||||||||
| Drives_construct | WBCnstr00000668 | ||||||||
| WBCnstr00000924 | |||||||||
| WBCnstr00012439 | |||||||||
| WBCnstr00037757 | |||||||||
| Construct_product | WBCnstr00009521 | ||||||||
| WBCnstr00009524 | |||||||||
| WBCnstr00012439 | |||||||||
| WBCnstr00037757 | |||||||||
| WBCnstr00038503 | |||||||||
| Antibody | WBAntibody00001783 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (209) | |||||||||
| Interaction (477) | |||||||||
| Map_info | Map | X | Position | -6.19992 | |||||
| Positive | Positive_clone | ACT13 | |||||||
| M03F4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Pseudo_map_position | |||||||||
| Reference (72) | |||||||||
| Remark | X -6.25 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
