WormBase Tree Display for Gene: RGD:62081
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RGD:62081 | Identity | Name | CGC_name | Hes1 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Public_name | Hes1 | |||||
DB_info | Database | RGD | id | 62081 | ||
AGR | cURI | RGD:62081 | ||||
EnsEMBL | ENSEMBL_geneID | ENSRNOG00000001720 | ||||
UniProt | UniProt_AC | Q04666 | ||||
Species | Rattus norvegicus | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00003008 | Caenorhabditis elegans | From_analysis | Inparanoid | ||
OrthoInspector | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | Enables several functions, including JUN kinase binding activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription corepressor binding activity. Involved in several processes, including cellular response to cytokine stimulus; regulation of gene expression; and regulation of gliogenesis. Located in nuclear matrix. Part of chromatin. Used to study chronic myeloid leukemia and epilepsy. Biomarker of acute kidney failure. Orthologous to human HES1 (hes family bHLH transcription factor 1); PARTICIPATES IN Notch signaling pathway; maturity-onset diabetes of the young pathway; Notch signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene. | Inferred_automatically | AGR_import |