WormBase Tree Display for Gene: RGD:3853
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| RGD:3853 | Identity | Name | CGC_name | Th | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Th | |||||
| DB_info | Database | RGD | id | 3853 | ||
| AGR | cURI | RGD:3853 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000020410 | ||||
| UniProt | UniProt_AC | P04177 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00000296 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| Structured_description | Automated_description | Enables several functions, including cation binding activity; oxygen binding activity; and tyrosine 3-monooxygenase activity. Involved in several processes, including aminergic neurotransmitter loading into synaptic vesicle; carboxylic acid metabolic process; and cellular response to nicotine. Located in several cellular components, including cytoplasmic vesicle; perikaryon; and terminal bouton. Used to study Parkinson's disease. Biomarker of several diseases, including brain disease (multiple); hyperprolactinemia; polycystic ovary syndrome; portal hypertension; and uremia. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinsonism; hypertension; and obesity. Orthologous to human TH (tyrosine hydroxylase); PARTICIPATES IN aromatic L-amino acid decarboxylase deficiency pathway; catecholamine biosynthetic pathway; dopamine biosynthetic pathway; INTERACTS WITH (+)-catechin; (+)-sesamin; (+)-taxifolin. | Inferred_automatically | AGR_import |
