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WormBase Tree Display for Gene: RGD:1566171

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Name Class

RGD:1566171IdentityNameCGC_nameMbtps2Inferred_automaticallyAGR_import
Public_nameMbtps2
DB_infoDatabaseRGDid1566171
AGRcURIRGD:1566171
EnsEMBLENSEMBL_geneIDENSRNOG00000007644
UniProtUniProt_ACA0A0G2K1S2
A0A8I6AN61
A0A8I6A7T1
D3ZDS6
Q4V8H3
A6IPP8
A6IPP9
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00013225Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionPredicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including bone maturation; membrane protein intracellular domain proteolysis; and mitotic G2 DNA damage checkpoint signaling. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in X-linked keratosis follicularis spinulosa decalvans; X-linked mutilating palmoplantar keratoderma with periorificial keratotic plaques; ichthyosis follicularis-alopecia-photophobia syndrome 1; and osteogenesis imperfecta type 19. Orthologous to human MBTPS2 (membrane bound transcription factor peptidase, site 2); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.Inferred_automaticallyAGR_import