WormBase Tree Display for Gene: HGNC:626
expand all nodes | collapse all nodes | view schema
| HGNC:626 | Identity | Name | CGC_name | Aprt | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:1317133 | |||||
| AMP | ||||||
| AMP diphosphorylase | ||||||
| AMP pyrophosphorylase | ||||||
| APRTD | ||||||
| DKFZp686D13177 | ||||||
| MGC125856 | ||||||
| MGC125857 | ||||||
| MGC129961 | ||||||
| transphosphoribosidase | ||||||
| Public_name | Aprt | |||||
| DB_info | Database | HGNC | id | 626 | ||
| AGR | cURI | HGNC:626 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000198931 | ||||
| UniProt | UniProt_AC | P07741 | ||||
| OMIM | gene | 102600 | ||||
| DO | id | DOID:0060350 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00020557 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |
