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WormBase Tree Display for Gene: HGNC:3313

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Name Class

HGNC:3313IdentityNameCGC_nameElavl2Inferred_automaticallyAGR_import
Other_name (11)
Public_nameElavl2
DB_infoDatabaseHGNCid3313
AGRcURIHGNC:3313
EnsEMBLENSEMBL_geneIDENSG00000107105
UniProtUniProt_ACQ12926
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00001368Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OMA
OrthoInspector
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionIn humans, the ELAV like RNA binding protein gene family has four members (ELAVL1-4). ELAVL RNA binding proteins recognize AU-rich elements in the 3' UTRs of gene transcripts and thereby regulate gene expression post-transcriptionally. The protein encoded by this gene binds to several 3' UTRs, including its own and also that of FOS, ID, and POU5F1. This gene encodes ELAVL2 and, like ELAVL3 and ELAVL4, is expressed specifically in neurons and primarily localizes to the cytoplasm. This protein also forms a cytosolic complex with the normally nuclear-localized ELAVL1 protein. Alternative splicing of this gene results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Jul 2020]Inferred_automaticallyAGR_import