WormBase Tree Display for Gene: HGNC:30788
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| HGNC:30788 | Identity (4) | |||||
|---|---|---|---|---|---|---|
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006773 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| OrthoFinder | ||||||
| Panther | ||||||
| Structured_description | Automated_description | This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] | Inferred_automatically | AGR_import |
