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WormBase Tree Display for Gene: HGNC:25127

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Name Class

HGNC:25127IdentityNameCGC_nameHnrnpllInferred_automaticallyAGR_import
Other_nameRGD:1353271
HNRPLL
SRRF
heterogeneous nuclear ribonucleoprotein L-like
stromal RNA regulating factor
stromal RNA-regulating factor
Public_nameHnrnpll
DB_infoDatabaseHGNCid25127
AGRcURIHGNC:25127
EnsEMBLENSEMBL_geneIDENSG00000143889
UniProtUniProt_ACQ8WVV9
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00016624Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionHNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]Inferred_automaticallyAGR_import