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WormBase Tree Display for Gene: HGNC:24353

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Name Class

HGNC:24353IdentityNameCGC_nameChtf8Inferred_automaticallyAGR_import
Other_nameRGD:1606282
CTF8
CTF8, chromosome transmission fidelity factor 8 homolog
Derpc
FLJ20400
chromosome transmission fidelity factor 8 homolog
chromosome transmission fidelity protein 8 homolog
decreased expression in renal and prostate cancer protein
hCTF8
Public_nameChtf8
DB_infoDatabaseHGNCid24353
AGRcURIHGNC:24353
EnsEMBLENSEMBL_geneIDENSG00000168802
UniProtUniProt_ACP0CG13
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00011915Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
Structured_descriptionAutomated_descriptionThis gene encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in both yeast and mammals. The heteroheptameric RFC complex plays a role in sister chromatid cohesion and may load the replication clamp PCNA (proliferating cell nuclear antigen) onto DNA during DNA replication and repair. This gene is ubiquitously expressed and has been shown to have reduced expression in renal and prostate tumors. Alternatively spliced transcript variants have been described. This gene has a pseudogene on chromosome X. [provided by RefSeq, Oct 2018]Inferred_automaticallyAGR_import