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WormBase Tree Display for Gene: HGNC:17007

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Name Class

HGNC:17007IdentityNameCGC_nameDusp14Inferred_automaticallyAGR_import
Other_nameRGD:1316598
MAP kinase phosphatase 6
MKP-1 like protein tyrosine phosphatase
MKP-1-like protein tyrosine phosphatase
MKP-6
MKP-L
MKP6
dual specificity protein phosphatase 14
mitogen-activated protein kinase phosphatase 6
Public_nameDusp14
DB_infoDatabaseHGNCid17007
AGRcURIHGNC:17007
EnsEMBLENSEMBL_geneIDENSG00000275932
ENSG00000276023
UniProtUniProt_ACO95147
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00007302Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionDual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]Inferred_automaticallyAGR_import