Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: HGNC:11391

expand all nodes | collapse all nodes | view schema

Name Class

HGNC:11391IdentityNameCGC_nameAurkcInferred_automaticallyAGR_import
Other_name (18)
Public_nameAurkc
DB_infoDatabaseHGNCid11391
AGRcURIHGNC:11391
EnsEMBLENSEMBL_geneIDENSG00000105146
UniProtUniProt_ACQ9UQB9
OMIMgene603495
DOidDOID:0070183
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00000099Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OMA
OrthoInspector
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import