WormBase Tree Display for Gene: HGNC:1076

HGNC:1076 Identity: Name: CGC_name: Bmpr1a Inferred_automatically: AGR_import
      Other_name (16)
      Public_name: Bmpr1a
    DB_info: Database: HGNC id 1076
        AGR cURI HGNC:1076
        EnsEMBL ENSEMBL_geneID ENSG00000107779
        UniProt UniProt_AC P36894
        OMIM gene 601299
        DO id DOID:5295
            DOID:0050787
            DOID:0111686
            DOID:6432
    Species: Homo sapiens
    Status: Live
  Gene_info: Biotype: SO:0001217
    Ortholog: WBGene00004860 Caenorhabditis elegans From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008] Inferred_automatically: AGR_import