WormBase Tree Display for Gene: HGNC:1069
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| HGNC:1069 | Identity | Name | CGC_name | Bmp2 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:733110 | |||||
| BDA2 | ||||||
| BMP-2A | ||||||
| bmp2a | ||||||
| SSFSC | ||||||
| SSFSC1 | ||||||
| bone morphogenetic protein 2A | ||||||
| Public_name | Bmp2 | |||||
| DB_info | Database | HGNC | id | 1069 | ||
| AGR | cURI | HGNC:1069 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000125845 | ||||
| UniProt | UniProt_AC | P12643 | ||||
| OMIM | gene | 112261 | ||||
| DO | id | EFO:MONDO:0031439 | ||||
| DOID:0110965 | ||||||
| DOID:11476 | ||||||
| DOID:10286 | ||||||
| DOID:10283 | ||||||
| DOID:12185 | ||||||
| DOID:0050591 | ||||||
| DOID:8398 | ||||||
| DOID:0111029 | ||||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00000936 | Caenorhabditis elegans | From_analysis | OrthoFinder | ||
| OrthoInspector | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016] | Inferred_automatically | AGR_import |
