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WormBase Tree Display for Gene: WBGene00001749

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Name Class

WBGene00001749EvidencePerson_evidenceWBPerson1846
SMapS_parentSequenceR107
IdentityVersion1
Name (5)
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgst
Allele (13)
Legacy_information[C.elegansII] NMK. Encodes predicted glutathione-S-transferase P subunit. Transpliced to SL2. [Weston et al. 1989]
RNASeq_FPKM (74)
GO_annotation (18)
Contained_in_operonCEOP3572
Ortholog (31)
Paralog (45)
Structured_descriptionConcise_descriptiongst-1 encodes a putative glutathione S-transferase of the pi class;GST-1 is required for sperm to normally migrate towards a PUFA-basedsignal exuded by oocytes; gst-1(RNAi) hermaphrodites are infertile,both through aberrant loss of their own sperm and through failure ofmales to effectively inseminate them.Paper_evidenceWBPaper00028527
Curator_confirmedWBPerson48
WBPerson567
Date_last_updated12 Mar 2007 00:00:00
Automated_descriptionEnables glutathione transferase activity. Involved in cellular detoxification; defense response to other organism; and regulation of cellular response to manganese ion. Predicted to be located in cytosol. Expressed in DA neuron. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (137)
Molecular_infoCorresponding_CDSR107.7
Corresponding_transcriptR107.7.1
Other_sequence (57)
Associated_featureWBsf645457
WBsf645458
WBsf645459
WBsf981541
WBsf993558
WBsf225512
Experimental_infoRNAi_result (11)
Expr_patternExpr11048
Expr1018206
Expr1031042
Expr1155346
Expr2012303
Expr2030539
Drives_constructWBCnstr00019132
WBCnstr00036720
Construct_productWBCnstr00036720
AntibodyWBAntibody00002442
Microarray_results (22)
Expression_cluster (205)
Interaction (46)
Map_infoMapIIIPosition0.129472Error0.002939
PositivePositive_cloneR107Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001135
WBPaper00006465
WBPaper00014145
WBPaper00015440
WBPaper00025088
WBPaper00028482
WBPaper00028527
WBPaper00028883
WBPaper00031973
WBPaper00036144
WBPaper00038491
WBPaper00039536
WBPaper00041581
WBPaper00042451
WBPaper00048395
WBPaper00049204
WBPaper00049477
WBPaper00049828
WBPaper00055090
WBPaper00058783
WBPaper00059551
WBPaper00059994
WBPaper00066052
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene